Publications

Latest Publications

2024

  • Rebecca Kristina E, Lavanya Prakash A, Sujay K. Maity , Partha Chakrabarti, Om Tantia, Manjunath B. Joshi, Kapaettu Satyamoorthy, Kishore V.L. Parsa, Parimal Misra (2024). TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice. BBA Molecular Basis of Disease, 1870: 166896. https://doi.org/10.1016/j.bbadis.2023.166896
  • Naga Lakshmi Challa, Ankita Sarkar, Satyamoorthy Kapettu, Prakash Babu Phanithi, Partha Chakrabarti, Kishore VL Parsa, Parimal Misra (2024). TGS1/PIMT regulates pro-inflammatory macrophage mediated paracrine insulin resistance: Crosstalk between macrophages and skeletal muscle cells, BBA Molecular Basis of Disease, 1870: 166878, www.elsevier.com/locate/bbadis https://doi.org/10.1016/j.bbadis.2023.166878.

2023

  • Sandeep Chakraborty, C. Saha (2023). A multi-tier computational screening framework to effectively search the mutational space of SARS-CoV-2 receptor binding motif to identify mutants with enhanced ACE2 binding abilities. Molecular Informatics, 42, e202300055.
  • MattaM, Deepti K, Bhuvan Tej M, Bhagya Tej M, Gopi Reddy A, Ravikumar K, Deepak Kumar B, Basaveswara Rao MV, Manojit Pal (2023). Ultrasound assisted Cu-catalyzed Ullmann-Goldberg type coupling-cyclization in a single pot: Synthesis and in silico evaluation of 11H-pyrido[2,1-b] quinazolin-11-ones against SARS-CoV-2 RdRp. Journal of Molecular Structure, 1280: 135044. https://doi.org/10.1016/j.molstruc.2023.135044
  • Rahul Aich, Prasun Pal, Sandipan Chakraborty, Biman Jana (2023). Preferential Ordering and Organization of Hydration Water Favor Nucleation of Ice by Ice-Nucleating Proteins over Antifreeze Proteins. The Journal of Physical Chemistry B, 127: 6038-6048.
  • Harshavardhan Bhuktar, Sharda Shukla, Kumar Reddy K, Srikanth Battu, Manupati Srikanth, Susmita Srivastava, Raghavender Medishetti, Pooja Ram, Jagadish PC, Mahaboobkhan Rasool, Sandipan Chakraborty, Nooruddin Khan, Pallu Reddanna, Srinivas Oruganti, Manojit Pal (2023). Design, synthesis and evaluation of 2-aryl quinoline derivatives against 12R-lipoxygenase (12R-LOX): Discovery of first inhibitor of 12R-LOX. Bioorganic Chemistry, 138: 106606. https://doi.org/10.1016/j.bioorg.2023.106606
  • Sharma R, Maity SK, Chakrabarti P, Katika MR, Kapettu S, Parsa KVL, Misra P (2023). PIMT controls insulin synthesis and secretion through PDX1. International Journal of Molecular Sciences, 24, 8084. https://doi.org/ 10.3390/ijms24098084.
  • Kanika Chandra, Swathi M, Keerthana B, Sooraj Gopan, Jyothi Priyanka Ghantasala Manjunath B Joshi, Manjunatha Thondamal, Kishore VLP (2023). PHLPP1 regulates PINK1-parkin signalling and life span, BBA – Molecular Basis of Disease, BBA-Molecular Basis of Disease, 1869: 166718, https://doi.org/10.1016/j.bbadis.2023.166718.
  • Raghavender Medishetti, Mallikarjuna Rao, Kiranam Chatti (2023). Cabozantinib‐induced edema in zebrafish represents an adverse effect characterized by defects in lymphatic vasculature and renal function, Journal of Biochemical and Molecular Toxicology, 37: e23413, https://doi.org/10.1002/jbt.23413.
  • Bandish K, Soma B, Sireesh TK, Partha C, Parsa KVL, Misra P (2023). PIMT regulates hepatic gluconeogenesis in mice, 26 (3), 106120, https://doi.org/10.1016/ j.isci.2023.106120
  • Sharda Shukla, R. Nishanth Rao, Harshavardhan Bhuktar, Rebecca Kristina Edwin, Trinath Jamma, Raghavender Medishetti, Sharmistha Banerjee, Varadaraj Bhat Giliyaru, Gautham G. Shenoy, Srinivas Oruganti, Parimal Misra, Manojit Pal (2023). Wang resin catalysed sonochemical synthesis of pyrazolo[4,3-d]pyrimidinones and 2,3-dihydroquinazolin-4(1H)-ones: Identification of chorismate mutase inhibitors having effects on Mycobacterium tuberculosis cell viability. Bioorganic Chemistry, 106452 https://doi.org/10.1016/j.bioorg.2023.106452.
  • Sowmya Ramaswamy Krishnan, Navneet Bung, Siladitya Padhi, Gopalakrishnan Bulusu, Parimal Misra, Manojit Pal, Srinivas Oruganti, Rajgopal Srinivasan, Arijit Roy. De novo design of anti-tuberculosis agents using a structure-based deep learning method (2023). Journal of Molecular Graphics and Modelling, 118: 108361 https://doi.org/10.1016/j.jmgm.2022.108361.
  • Sailaja Garrepalli, Ramesh Gudipati, Ravikumar Kapavarapu, Kunta Ravindhranath, Manojit Pal (2023). Synthesis and characterization of two known and one new impurities of dolutegravir: In silico evaluation of certain intermediates against SARS CoV-2 O-ribose methyltransferase (OMTase). Journal of Molecular Structure, 1271:133992.

2022

  • Thirupataiah B, Bhuktar H, Mounika G, Reddy GS, Kumar JS, Shukla S, Hossain KA, Medishetti R, Samarpita S, Rasool M, Jagadish PC, Shenoy GG, Parsa KVL, Pal M (2022). Sonochemical synthesis and biological evaluation of isoquinolin-1(2H)-one/isoindolin-1-one derivatives: Discovery of a positive ago-allosteric modulator (PAAM) of 5HT2CR. Bioorganic Chemistry, 121:105667.
  • Prasun Pal, Rahul Aich, Sandipan Chakraborty, Biman Jana (2022). Molecular factors of ice growth inhibition for hyperactive and globular antifreeze protein: Insights from molecular dynamics simulation. Langmuir, 38, 49, 151-32-15144.
  • Sujeevan Reddy G, Sandeep Kumar J, Thirupataiah B, Bhuktar H, Shukla S, Pal M (2022). Recent advances in transition metal-catalyzed reactions of chloroquinoxalines: Applications in bioorganic chemistry. Bioorganic Chemistry, 129:106195.
  • Prasun Pal, Sandipan Chakraborty, and Biman Jana (2022). Number of Hydrogen Bonds per Unit Solvent Accessible Surface Area: A Descriptor of Functional States of Proteins. The Journal of Physical Chemistry virtual special issue, https://doi.org/10.1021/acs.jpcc.2c06093
  • Raghavendra Medishetti, Keerthana Balamurugan, Krishnaveni Yadavalli, Rita Rani, Aarti Sevilimedu, Anil Kumar Chella, Kishore Parsa, Kiranam Chatti (2022). CRISPR-Cas9-induced gene knockout in zebrafish. STAR Protocols, 3 (4): 101779. DOI: https://doi.org/10.1016/j.xpro.2022.101779.
  • Keerthana Balamurugan, Raghavendra Medishetti, Pallavi Rao, Rahul Varma K, Kiranam Chatti, Kishore Parsa (2022). Protocol to evaluate hyperlipidemia in zebrafish larvae. STAR Protocols, 3 (4), 101819. DOI: https://doi.org/10.1016/j.xpro.2022.101819
  • Keerthana Balamurugan, Kanika Chandra, Sai Latha S, Swathi M, Manjunath B. Joshi, Parimal Misra, Kishore V. L. Parsa (2022). PHLPPs: Emerging players in metabolic disorders. Drug Discovery Today, 27 (10), 103317. DOI: https://doi.org/10.1016/j.drudis.2022.07.002
  • Sandipan Chakraborty, Sanjana Ghosh, Trisha Mondal (2022). Decoding molecular factors shaping human angiotensin converting enzyme 2 receptor usage by spike glycoprotein in lineage B beta-coronaviruses. BBA–Molecular Basis of Disease, 1868, pg 166514. https://doi.org/10.1016/j.bbadis.2022.166514.
  • Srijon Ghosh, Sandipan Chakraborty, Arnab Ghosh, Kritiman Marjit, Goutam Ghosh, and Amitava Patra (2022). Ultrafast relaxation dynamics of conjugated polymer nanoparticles by tuning their interchain interactions cite. The Journal of Physical Chemistry,  https://doi.org/10.1021/acs.jpcc.2c06093.
  • Gangireddy Sujeevan Reddy, Sharda Shukla, Harshavardhan Bhuktar, Kazi Amirul Hossain, Rebecca Kristina Edwin, Varadaraj Bhat Giliyaru, Parimal Misra and Manojit Pal (2022). Pd/Cu-catalyzed access to novel 3-(benzofuran-2-ylmethyl) substituted (pyrazolo / benzo) triazinone derivatives: Their in silico / in vitro evaluation as inhibitors of chorismate mutase (CM). RSC Advances (IN PRESS).
  • Sandipan Chakraborty, Aditi Saha, Chiranjeet Saha, Sanjana Ghosh, Trisha Mondal (2022). Decoding the effects of spike receptor binding domain mutations on antibody escape abilities of omicron variants. Biochemical and Biophysical Research Communications, 627: 168-175.
  • Ramesh Samineni, Vishnuvardhan Eda, Pallavi Rao, Saketh Sen, Srinivas Oruganti (2022). Grinard reagents as niche bases in the synthesis of pharmaceutically relevant molecules. ChemistrySelect, 7 (5), DOI: https://doi.org/10.1002/slct.202102853
  • Rani R, Parsa KVL, Kiranam C, Sevelimedu A (2022). An efficient cost-effective method for directed mutagenesis at multiple dispersed sites-a case study with Omicron spike DNA. bioRxiv. DOI: https://doi.org/10.1101/2022.02.10.480017.
  • Thirupataiah B, Harshavardhan Bhuktar, Guntipally Mounika, Gangireddy Sujeevan Reddy, Jetta Sandeep Kumar, Sharda Shukla, Kazi Amirul Hossain, Raghavender Medishetti, Snigdha Samarpita, Mahaboobkhan Rasool, PC Jagadish, Gautham G Shenoy, Kishore VL Parsa, Manojit Pal (2022). Fe (III)-catalyzed regioselective and faster synthesis of isocoumarins with 3-oxoalkyl moiety at C-4: Identification of new inhibitors of PDE4. Bioorganic chemistry, 121, 105667. DOI: https://doi.org/10.1016/j.bioorg.2022.105667.
  • Keerthana B, Raghavender Medishetti, Jyothi Kotha, Parameshwar Behera, Kanika Chandra, Vijay Aditya Mavuduru, Manjunath B Joshi, Ramesh Samineni, Madhumohan R Katika, Writoban Basu Bal, Manjunatha Thondamal, Anil Challa, Kiranam Chatti, Kishore VL Parsa (2022). PHLPP1 promotes neutral lipid accumulation through AMPK/ChREBP dependent lipid uptake and fatty acid synthesis pathways. iScience, 25 (2), 103766. DOI: https://doi.org/10.1016/j.isci.2022.103766.
  • Rebecca Kristina Edwin, Nagalakshmi Challa, Rahul Sharma, Satyamoorthy K, Kishore Parsa, Parimal Misra (2022). PIMT/TGS1: An evolving metabolic molecular switch with conserved methyl transferase activity. Drug Discovery Today, https://doi.org/10.1016/j.drudis.2022.04.018.
  • Jetta Sandeep Kumar, Gangireddy Sujeevan Reddy, Raghavender Medishetti, Kazi Amirul Hossain, B. Thirupataiah, Jhansi Edelli, Shilpak Dilip Bele, Rebecca Kristina Edwin, Alex Joseph, Gautham G. Shenoy, C. Mallikarjuna Rao, Manojit Pal (2022). Ultrasound assisted one-pot synthesis of rosuvastatin based novel azaindole derivatives via coupling-cyclization strategy under Pd/Cu-catalysis: their evaluation as potential cytotoxic agents. Bioorganic Chemistry 105857; https://doi.org/10.1016/j.bioorg.2022.105857

 Complete year-wise list can be found here : Publications for DRILS