2021
- Carlone Armando, Bernardi Luca, McCormack Peter, Warr Tony, Oruganti Srinivas, Cobley Christopher J (2021). Asymmetric Organocatalysis and Continuous Chemistry for an Efficient and Cost-Competitive Process to Pregabalin. Organic Process Research & Development, 25 (12): 2795-2805.
- Challa, C.S., Katari, N.K., Nallanchakravarthula, V., Nayakanti, D., Kapavarapu, R., Pal, M. Sonochemical synthesis of 2-substituted nicotinic acid ethyl ester derivatives: Their in vitro and in silico evaluation against SIRT1 (2021) Journal of Molecular Structure, 1245. DOI: 10.1016/j.molstruc.2021.131069
- Reddy, G.S., Kamaraj, R., Hossain, K.A., Kumar, J.S., Thirupataiah, B., Medishetti, R., Sushma Sri, N., Misra, P., Pal, M. Amberlyst-15 catalysed synthesis of novel indole derivatives under ultrasound irradiation: Their evaluation as serotonin 5-HT2C receptor agonists (2021) Bioorganic Chemistry, 116. DOI: 10.1016/j.bioorg.2021.105380
- Thirupataiah, B., Reddy, G.S., Mounika, G., Kumar, J.S., Hossain, K.A., Mudgal, J., Mathew, J.E., Shenoy, G.G., Rajadurai, M., Parsa, K.V.L., Pal, M. Pd-catalysed general access to 7-membered N/O-heterocyclic compounds as potential agents against inflammation (2021) Chemical Communications, 57 (78), pp. 10091-10094. DOI: 10.1039/d1cc04140a
- Thirupataiah, B., Mounika, G., Reddy, G.S., Kumar, J.S., Hossain, K.A., Medishetti, R., Samarpita, S., Rasool, M., Mudgal, J., Mathew, J.E., Shenoy, G.G., Rao, C.M., Chatti, K., Parsa, K.V.L., Pal, M. PdCl2-catalyzed synthesis of a new class of isocoumarin derivatives containing aminosulfonyl / aminocarboxamide moiety: First identification of a isocoumarin based PDE4 inhibitor (2021) European Journal of Medicinal Chemistry, 221, art. no. 113514. DOI: 10.1016/j.ejmech.2021.113514
- Thirupataiah, B., Mounika, G., Sujeevan Reddy, G., Sandeep Kumar, J., Kapavarapu, R., Medishetti, R., Mudgal, J., Mathew, J.E., Shenoy, G.G., Mallikarjuna Rao, C., Chatti, K., V. L. Parsa, K., Pal, M. CuCl2-catalyzed inexpensive, faster and ligand/additive free synthesis of isoquinolin-1(2H)-one derivatives via the coupling–cyclization strategy: Evaluation of a new class of compounds as potential PDE4 inhibitors (2021) Bioorganic Chemistry, 115. DOI: 10.1016/j.bioorg.2021.105265
- Challa, C.S., Katari, N.K., Nallanchakravarthula, V., Nayakanti, D., Kapavarapu, R., Pal, M. Amberlyst-15 catalysed sonochemical synthesis of 2-amino-4,6-disubstituted nicotinonitrile derivatives and their biological evaluation (2021) Journal of Molecular Structure, 1240. DOI: 10.1016/j.molstruc.2021.130541
- Kumar, J.S., Reddy, G.S., Medishetti, R., Ray, A., Bele, S.D., Hossain, K.A., Thirupataiah, B., Edwin, R.K., Behera, P., Joseph, A., Shenoy, G.G., Rao, C.M., Pal, M. Sonochemical synthesis of rosuvastatin based novel 3-methyleneisoindolin-1-one derivatives as potential anticancer agents (2021) Journal of Molecular Structure, 1240. DOI: 10.1016/j.molstruc.2021.130574
- Sujeevan Reddy, G., Sandeep Kumar, J., Thirupataiah, B., Amirul Hossain, K., Babu Nallapati, S., Bhat Giliyaru, V., Chandrashekhar Hariharapura, R., Gautham Shenoy, G., Pal, M. Propargylamines in Pd/Cu-catalyzed tandem coupling-cyclization-N-deprotection in a single pot: Construction of N-unsubstituted vs N-sulfonyl indole ring (2021) Tetrahedron Letters, 77. DOI: 10.1016/j.tetlet.2021.153213
- Satyanarayana, M.V., Reddy, A.G., Yedukondalu, M., Tej, M.B., Hossain, K.A., Rao, M.V.B., Pal, M. In silico assessment and sonochemical synthesis of 2-alkynyl 3-chloropyrazines as prospective ligands for SARS-CoV-2 (2021) Journal of Molecular Structure, 1231. DOI: 10.1016/j.molstruc.2021.129981
- Kandula, V.R., Pothireddy, M., Babu, K.S., Kapavarapu, R., Dandela, R., Pal, M. Sonochemical synthesis of polyarylated oxazoles as potential cytotoxic agents (2021) Tetrahedron Letters, 70. DOI: 10.1016/j.tetlet.2021.153011
- Chemboli, R., Kapavarapu, R., Deepti, K., Prasad, K.R.S., Reddy, A.G., Kumar, A.V.D.N., Rao, M.V.B., Pal, M. Pyrrolo[2,3-b] quinoxalines in attenuating cytokine storm in COVID-19: their sonochemical synthesis and in silico / in vitro assessment (2021) Journal of Molecular Structure, 1230. DOI: 10.1016/j.molstruc.2020.129868
- Kumar Mallurwar, N., Khatravath, M., Konda, S., Thatikonda, T., Iqbal, J., Arya, P. Stereoselective Approaches for Building the C14-C21 Fragment of Eribulin (2021) Chemistry Select, 6 (4), pp. 798-801. DOI: 10.1002/slct.202004001
- Venkata Basaveswara Rao, M., Veera Durga Rao, B., Vijaya Vardhini, S., Nagendra Kumar, A.V.D., Rao Gorja, D., Kapavarapu, R., Pal, M. In Silico and Biological Evaluation of N-(2-methoxyphenyl) Substituted Pyrazoles Accessed via a Sonochemical Method (2021) Chemistry Select, 6 (4), pp. 788-797. DOI: 10.1002/slct.202004586
2020
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Rao, M.V.B., SriLaxmi, D., Vardhini, S.V., Guttikonda, V.R., Kapavarapu, R., Pal, M. Sonochemical Synthesis of 6-Substituted Indolo[3′,2′:4,5]pyrrolo[2,3-b]quinoxaline Derivatives as Potential Cytotoxic Agents (2020) Chemistry Select, 5 (45), pp. 14239-14246. DOI: 10.1002/slct.202002951
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Shahinshavali, S., Hossain, K.A., Kumar, A.V.D.N., Reddy, A.G., Kolli, D., Nakhi, A., Rao, M.V.B., Pal, M. Ultrasound assisted synthesis of 3-alkynyl substituted 2-chloroquinoxaline derivatives: Their in silico assessment as potential ligands for N-protein of SARS-CoV-2 (2020) Tetrahedron Letters, 61 (40). DOI: 10.1016/j.tetlet.2020.152336
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Mitra, P. Inhibiting fusion with cellular membrane system: Therapeutic options to prevent severe acute respiratory syndrome coronavirus-2 infection (2020) American Journal of Physiology – Cell Physiology, 319 (3), pp. C500-C509. DOI: 10.1152/ajpcell.00260.2020
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Kumar, J.S., Thirupataiah, B., Medishetti, R., Ray, A., Bele, S.D., Hossain, K.A., Reddy, G.S., Edwin, R.K., Joseph, A., Kumar, N., Shenoy, G.G., Rao, C.M., Pal, M. Rosuvastatin based novel 3-substituted isocoumarins / 3-alkylidenephthalides: Ultrasound assisted synthesis and identification of new anticancer agents (2020) European Journal of Medicinal Chemistry, 201. DOI: 10.1016/j.ejmech.2020.112335
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Dhananjaya, G., Rao, A.V.D., Hossain, K.A., Anna, V.R., Pal, M. In silico studies and β-cyclodextrin mediated neutral synthesis of 4-oxo-4,5,6,7-tetrahydroindoles of potential biological interest (2020) Tetrahedron Letters, 61 (24). DOI: 10.1016/j.tetlet.2020.151972
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Venkateshwarlu, R., Nath Singh, S., Siddaiah, V., Ramamohan, H., Dandela, R., Amirul Hossain, K., Vijaya Babu, P., Pal, M. Ultrasound assisted rapid synthesis of mefenamic acid based indole derivatives under ligand free Cu-catalysis: Their pharmacological evaluation (2020) Bioorganic and Medicinal Chemistry Letters, 30 (10). DOI: 10.1016/j.bmcl.2020.127112
- Thirupataiah, B., Reddy, G.S., Ghule, S.S., Kumar, J.S., Mounika, G., Hossain, K.A., Mudgal, J., Mathew, J.E., Shenoy, G.G., Parsa, K.V.L., Pal, M. Synthesis of 11,12-dihydro benzo[c]phenanthridines via a Pd-catalyzed unusual construction of isocoumarin ring/FeCl3-mediated intramolecular arene-allyl cyclization: First identification of a benzo[c]phenanthridine based PDE4 inhibitor (2020) Bioorganic Chemistry, 97. DOI: 10.1016/j.bioorg.2020.103691
- Prasad, M.G., Lakshmi, C.V., Katari, N.K., Pal, M. Lemon juice as a biocatalyst under ultrasound irradiation: Synthesis and pharmacological evaluation of 2-amino 1,3,4-thiadiazoles (2020) Anti-Cancer Agents in Medicinal Chemistry, 20 (11), pp. 1379-1386. DOI: 10.2174/1871520620666200409143513
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Sri Laxmi, D., Vardhini, S.V., Guttikonda, V.R., Rao, M.V.B., Pal, M. Synthesis of 2-substituted furo[3,2-b]pyridines under pd/c-cu catalysis assisted by ultrasound: Their evaluation as potential cytotoxic agents (2020) Anti-Cancer Agents in Medicinal Chemistry, 20 (8), pp. 932-940. DOI: 10.2174/1871520620666200311102304
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Medishetti, R., Rani, R., Kavati, S., Mahilkar, A., Akella, V., Saxena, U., Kulkarni, P., Sevilimedu, A. A DNAzyme based knockdown model for Fragile-X syndrome in zebrafish reveals a critical window for therapeutic intervention (2020) Journal of Pharmacological and Toxicological Methods, 101. DOI: 10.1016/j.vascn.2019.106656
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Venkata Basaveswara Rao, M., Veera Durga Rao, B., Vijaya Vardhini, S., Nagendra Kumar, A.V.D., Rao Gorja, D., Kapavarapu, R., Pal, M. In Silico and Biological Evaluation of N-(2-methoxyphenyl) Substituted Pyrazoles Accessed via a Sonochemical Method (2021) Chemistry Select, 6 (4), pp. 788-797. DOI: 10.1002/slct.202004586
2019
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Venkateshwarlu, R., Nath Singh, S., Siddaiah, V., Ramamohan, H., Dandela, R., Pal, M. Ultrasound assisted one-pot synthesis of 1,2-diaryl azaindoles via Pd/C-Cu catalysis: Identification of potential cytotoxic agents (2019) Tetrahedron Letters, 60 (52). DOI: 10.1016/j.tetlet.2019.151326
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Rani, C.S., Suresh, N., Rao, M.V.B., Pal, M. Montmorillonite K10 catalyzed one-pot synthesis of 2-aryl substituted N-(4-oxo-1,2-dihydroquinazolin-3(4H)-yl) aryl or alkylamide derivatives under ultrasound irradiation (2019) Arabian Journal of Chemistry, 12 (8), pp. 3911-3920. DOI: 10.1016/j.arabjc.2016.02.014
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Bhavani, S., Ashfaq, M.A., Rambabu, D., Basaveswara Rao, M.V., Pal, M. Ultrasound assisted Mizoroki–Heck reaction catalyzed by Pd/C: Synthesis of 3-vinyl indoles as potential cytotoxic agents (2019) Arabian Journal of Chemistry, 12 (8), pp. 3836-3846. DOI: 10.1016/j.arabjc.2016.02.002
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Suresh, N., Prasanna, G.L., Ratnakar, A., Rao, M.V.B., Pal, M. An ultrasound-based approach for the synthesis of indoles under Pd/C catalysis (2019) Arabian Journal of Chemistry, 12 (8), pp. 5370-5379. DOI: 10.1016/j.arabjc.2017.01.007
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Prasad, A.S.G., Bhaskara Rao, T., Rambabu, D., Basaveswara Rao, M.V., Pal, M. Ultrasound assisted Mizoroki–Heck coupling/C–H amination in a single pot: Direct synthesis of indole derivatives (2019) Arabian Journal of Chemistry, 12 (8), pp. 4320-4330. DOI: 10.1016/j.arabjc.2016.06.004
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Bhavani, S., Rambabu, D., Rao, M.V.B., Pal, M. Ultrasound assisted site-selective alkynylation of 2,3,5,6-tetrachloropyridines under Pd/C[sbnd]Cu catalysis (2019) Arabian Journal of Chemistry, 12 (8), pp. 4189-4196. DOI: 10.1016/j.arabjc.2016.05.003
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Suresh, N., Prasanna, G.L., Rao, M.V.B., Pal, M. Ultrasound assisted synthesis of 6-flavonyl substituted 1,4-dihydro-benzo[d][1,3]oxazin-2-ones via Suzuki–Miyaura coupling under Pd/C catalysis (2019) Arabian Journal of Chemistry, 12 (8), pp. 4220-4230. DOI: 10.1016/j.arabjc.2016.05.009
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Sailaja, E., Bhavani, S., Rambabu, D., Basaveswara Rao, M.V., Pal, M. A greener approach toward N − 1 heteroarylation of indoles: Synthesis and in vitro evaluation of potential anti-proliferative agents (2019) Arabian Journal of Chemistry, 12 (8), pp. 3667-3677. DOI: 10.1016/j.arabjc.2015.11.008
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Luther, B.J., Rani, C.S., Suresh, N., Basaveswara Rao, M.V., Kapavarapu, R., Suresh, C., Vijaya Babu, P., Pal, M. Design and synthesis of novel indole-quinoxaline hybrids to target phosphodiesterase 4 (PDE4) (2019) Arabian Journal of Chemistry, 12 (8), pp. 3108-3117. DOI: 10.1016/j.arabjc.2015.08.009
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Vijaya Babu, P., Ashfaq, M.A., Shiva Kumar, K., Mukkanti, K., Pal, M. Mefenamic acid based novel indole analogues: Their synthesis and anti-proliferative effects (2019) Arabian Journal of Chemistry, 12 (8), pp. 2749-2759. DOI: 10.1016/j.arabjc.2015.05.018
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Rao, M.S., Haritha, M., Chandrasekhar, N., Basaveswara Rao, M.V., Pal, M. Ultrasound mediated synthesis of 6-substituted 2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinoline derivatives and their pharmacological evaluation (2019) Arabian Journal of Chemistry, 12 (8), pp. 2697-2703. DOI: 10.1016/j.arabjc.2015.05.013
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Reddy, G.S., Snehalatha, A.V., Edwin, R.K., Hossain, K.A., Giliyaru, V.B., Hariharapura, R.C., Gautham Shenoy, G., Misra, P., Pal, M. Synthesis of 3-indolylmethyl substituted (pyrazolo/benzo)triazinone derivatives under Pd/Cu-catalysis: Identification of potent inhibitors of chorismate mutase (CM) (2019) Bioorganic Chemistry, 91. DOI: 10.1016/j.bioorg.2019.103155
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Khatravath, M., Mallurwar, N.K., Konda, S., Gaddam, J., Rao, P., Iqbal, J., Arya, P. Synthesis of C1–C11 eribulin fragment and its diastereomeric analogues (2019) Tetrahedron Letters, 60 (37). DOI: 10.1016/j.tetlet.2019.07.006
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Sunke, R., Bankala, R., Thirupataiah, B., Ramarao, E.V.V.S., Kumar, J.S., Doss, H.M., Medishetti, R., Kulkarni, P., Kapavarapu, R.K., Rasool, M., Mudgal, J., Mathew, J.E., Shenoy, G.G., Parsa, K.V.L., Pal, M. InCl3 mediated heteroarylation of indoles and their derivatization via C[sbnd]H activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis (2019) European Journal of Medicinal Chemistry, 174, pp. 198-215. DOI: 10.1016/j.ejmech.2019.04.020
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Reddy, G.S., Hossain, K.A., Kumar, J.S., Thirupataiah, B., Edwin, R.K., Giliyaru, V.B., Chandrashekhar Hariharapura, R., Shenoy, G.G., Misra, P., Pal, M. Novel isatin-indole derivatives as potential inhibitors of chorismate mutase (CM): Their synthesis along with unexpected formation of 2-indolylmethylamino benzoate ester under Pd-Cu catalysis (2019) RSC Advances, 10 (1), pp. 289-297. DOI: 10.1039/c9ra09236f
2018
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Sujeevan Reddy, G., Babu Nallapati, S., Sri Saranya, P.S.V.K., Sridhar, B., Bhat Giliyaru, V., Chandrashekhar Hariharapura, R., Gautham Shenoy, G., Pal, M. Propargylamine (secondary) as a building block in indole synthesis involving ultrasound assisted Pd/Cu-catalyzed coupling-cyclization method: Unexpected formation of (pyrazole)imine derivatives (2018) Tetrahedron Letters, 59 (52), pp. 4587-4592. DOI: 10.1016/j.tetlet.2018.11.037
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Bung, N., Surepalli, S., Seshadri, S., Patel, S., Peddasomayajula, S., Kummari, L.K., Kumar, S.T., Babu, P.P., Parsa, K.V.L., Poondra, R.R., Bulusu, G., Misra, P. 2-[2-(4-(trifluoromethyl) phenylamino)thiazol-4-yl]acetic acid (Activator-3) is a potent activator of AMPK (2018) Scientific Reports, 8 (1). DOI: 10.1038/s41598-018-27974-1
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Marepu, N., Yeturu, S., Pal, M. 1,2,3-Triazole fused with pyridine/pyrimidine as new template for antimicrobial agents: Regioselective synthesis and identification of potent N-heteroarenes (2018) Bioorganic and Medicinal Chemistry Letters, 28 (20), pp. 3302-3306. DOI: 10.1016/j.bmcl.2018.09.021
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Marepu, N., Yeturu, S., Pal, M. Synthesis and Cytotoxicity of (±)-9-Hydroxy-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-2-carboxamide: An Active Component of Juglans regia (2018) Asian Journal of Organic Chemistry, 7 (9), pp. 1806-1809. DOI: 10.1002/ajoc.201800425
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Krishna, S., Chatti, K., Galigekere, R.R. Automatic and Robust Estimation of Heart Rate in Zebrafish Larvae (2018) IEEE Transactions on Automation Science and Engineering, 15 (3), pp. 1041-1052. DOI: 10.1109/TASE.2017.2705240
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Gade, N.R., Iqbal, J. Natural Product Inspired Topology Directed Synthesis of Hybrid Macrocyclic Compounds: A Simple Approach to Natural Product Analogues (2018) Chemistry Select, 3 (22), pp. 6262-6266. DOI: 10.1002/slct.201801117
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Behera, S., Kapadia, B., Kain, V., Alamuru-Yellapragada, N.P., Murunikkara, V., Kumar, S.T., Babu, P.P., Seshadri, S., Shivarudraiah, P., Hiriyan, J., Gangula, N.R., Maddika, S., Misra, P., Parsa, K.V.L. ERK1/2 activated PHLPP1 induces skeletal muscle ER stress through the inhibition of a novel substrate AMPK (2018) Biochimica et Biophysica Acta – Molecular Basis of Disease, 1864 (5), pp. 1702-1716. DOI: 10.1016/j.bbadis.2018.02.019
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Guduru, S.K.R., Arya, P. Synthesis and biological evaluation of rapamycin-derived, next generation small molecules (2018) Medicinal Chemistry Communications, 9 (1), pp. 27-43 DOI: 10.1039/c7md00474e
2017
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Girada, S.B., Kuna, R.S., Bele, S., Zhu, Z., Chakravarthi, N.R., DiMarchi, R.D., Mitra, P. Gαs regulates Glucagon-Like Peptide 1 Receptor-mediated cyclic AMP generation at Rab5 endosomal compartment (2017) Molecular Metabolism, 6 (10), pp. 1173-1185. DOI: 10.1016/j.molmet.2017.08.002
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Ghosh, A., Sengupta, A., Seerapu, G.P.K., Nakhi, A., Shivaji Ramarao, E.V.V., Bung, N., Bulusu, G., Pal, M., Haldar, D. A novel SIRT1 inhibitor, 4bb induces apoptosis in HCT116 human colon carcinoma cells partially by activating p53 (2017) Biochemical and Biophysical Research Communications, 488 (3), pp. 562-569. DOI: 10.1016/j.bbrc.2017.05.089
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Alamuru-Yellapragada, N.P., Kapadia, B., Parsa, K.V.L. In-house made nucleofection buffer for efficient and cost effective transfection of RAW 264.7 macrophages (2017) Biochemical and Biophysical Research Communications, 487 (2), pp. 247-254. DOI: 10.1016/j.bbrc.2017.04.043
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Alamuru-Yellapragada, N.P., Vundyala, S., Behera, S., Parsa, K.V.L. LPS depletes PHLPP levels in macrophages through the inhibition of SP1 dependent transcriptional regulation (2017) Biochemical and Biophysical Research Communications, 486 (2), pp. 533-538. DOI: 10.1016/j.bbrc.2017.03.080
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Kumar, A., Rani, M., Ehtesham, N.Z., Hasnain, S.E. Commentary: Modification of host responses by mycobacteria (2017) Frontiers in Immunology, 8 (APR). DOI: 10.3389/fimmu.2017.0046
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Talari, M., Nayak, T.K.S., Kain, V., Babu, P.P., Misra, P., Parsa, K.V.L. MicroRNA-712 restrains macrophage pro-inflammatory responses by targeting LRRK2 leading to restoration of insulin stimulated glucose uptake by myoblasts (2017) Molecular Immunology, 82, pp. 1-9. DOI: 10.1016/j.molimm.2016.12.014
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Nayak, T.K.S., Alamuru-Yellapragada, N.P., Parsa, K.V.L. Deubiquitinase USP12 promotes LPS induced macrophage responses through inhibition of IκBα (2017) Biochemical and Biophysical Research Communications, 483 (1), pp. 69-74. DOI: 10.1016/j.bbrc.2017.01.004
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Reddy, E.R., Yaseen, A.M., Rizvi, A., Deora, G.S., Banerjee, S., Sevilimedu, A., Rajadurai, M. Antibacterial Nanoparticles Based on Fluorescent 3-Substituted Uridine Analogue (2017) Chemistry Select, 2 (1), pp. 557-561. DOI: 10.1002/slct.201601708
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Bharath, Y., Rao, M.V.B., Pal, M. Ultrasound assisted synthesis of 2-alkynyl pyrazolo[1,5-a] pyrimidines as potential anti-cancer agents (2017) Letters in Drug Design and Discovery, 14 (10), pp. 1206-1214. DOI: 10.2174/1570180814666170125125654
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Prasad, A.S.G., Bhaskara Rao, T., Rambabu, D., Rao, M.V.B., Pal, M. Ultrasound assisted faster and milder approach to 6h-pyrido[1,2-a] quinazolin-6-imine derivatives as potential inhibitors of PDE4 (2017) Letters in Drug Design and Discovery, 14 (10), pp. 1184-1194. DOI: 10.2174/157018081466617031712551
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Suresha, N., Durgaraoa, B.V., Ratnakar, A., Kolli, S.K., Ashfaq, M.A., Rao, M.V.B., Pal, M. Ultrasound-assisted 3-component reaction in acetic acid alone: Catalyst/promoter/ligand free synthesis of bioactive pyrazolo[1,5-a]pyrimidines (2017) Letters in Drug Design and Discovery, 14 (10), pp. 1176-1183. Cited 3 times. DOI: 10.2174/1570180814666170126120408
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Sunke, R., Nallapati, S.B., Kumar, J.S., Shiva Kumar, K., Pal, M. Use of AlCl3 in Friedel Crafts arylation type reactions and beyond: An overview on the development of unique methodologies leading to N-heteroarenes (2017) Organic and Biomolecular Chemistry, 15 (19), pp. 4042-4057. DOI: 10.1039/c7ob00468k
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Kallam, S.R., Eda, V.R., Sen, S., Datrika, R., Rapolu, R.K., Khobare, S., Gajare, V., Banda, M., Khan, R.A.R., Singh, M., Lloyd, M., Kandagatla, B., Janagili, M.B., Tadikonda, V.P., Vidavalur, S., Iqbal, J., Fox, M.E., Dahanukar, V.H., Oruganti, S. A diastereoselective synthesis of boceprevir’s gem-dimethyl bicyclic [3.1.0] proline intermediate from an insecticide ingredient cis-cypermethric acid (2017) Tetrahedron, 73 (30), pp. 4285-4294. DOI: 10.1016/j.tet.2017.05.080
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Jogula, S., Soorneedi, A.R., Gaddam, J., Chamakuri, S., Deora, G.S., Indarapu, R.K., Ramgopal, M.K., Dravida, S., Arya, P. Geldanamycin-inspired compounds induce direct trans-differentiation of human mesenchymal stem cells to neurons (2017) European Journal of Medicinal Chemistry, 135, pp. 110-116. DOI: 10.1016/j.ejmech.2017.03.082
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Khanapur, M., Alvala, M., Prabhakar, M., Shiva Kumar, K., Edwin, R.K., Sri Saranya, P.S.V.K., Patel, R.K., Bulusu, G., Misra, P., Pal, M. Mycobacterium tuberculosis chorismate mutase: A potential target for TB (2017) Bioorganic and Medicinal Chemistry, 25 (6), pp. 1725-1736. DOI: 10.1016/j.bmc.2017.02.001
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Kumar, K.S., Bhaskar, B., Ramulu, M.S., Kumar, N.P., Ashfaq, M.A., Pal, M. Metal catalyst free cyclization of 3-alkynyl substituted 2-(indol-3-yl)quinoxalines in TFA alone: a new synthesis of indolophenazines (2017) Organic and Biomolecular Chemistry, 15 (1), pp. 82-87. DOI: 10.1039/c6ob02340a
2016
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Nallapati, S.B., Prasad, B., Sreenivas, B.Y., Sunke, R., Poornachandra, Y., Kumar, C.G., Sridhar, B., Shivashankar, S., Mukkanti, K., Pal, M. Apparent Carbon Monoxide Insertion via Double Isocyanide Incorporation during Palladium-Catalyzed Construction of Indoloquinoline Ring in a Single Pot: Synthesis of New Cytotoxic Agents (2016) Advanced Synthesis and Catalysis, 358 (21), pp. 3387-3393. DOI: 10.1002/adsc.201600599
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Sunke, R., Ramarao, E.V.V.S., Nallapati, S.B., Medisetti, R., Kulkarni, P., Kapavarapu, R.K., Bankala, R., Parsa, K.V.L., Pal, M. Copper-Catalyzed Domino Reaction Involving Nitro as an Unexpected Leaving Group: Construction of Dibenzo-Fused Azepinone Ring (2016) Advanced Synthesis and Catalysis, 358 (20), pp. 3201-3205. DOI: 10.1002/adsc.201600748
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Dasari, B., Fufa, T., Aeluri, M., Gaddam, J., Deora, G.S., Gaunitz, F., Kitambi, S.S., Arya, P. Macrocyclic Toolbox from Epothilone Fragment Identifies a Compound Showing Molecular Interactions with Actin and Novel Promoters of Apoptosis in Patient-derived Brain Tumor Cells (2016) Asian Journal of Organic Chemistry, 5 (8), pp. 976-980. DOI: 10.1002/ajoc.201600126
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Asalla, S., Girada, S.B., Kuna, R.S., Chowdhury, D., Kandagatla, B., Oruganti, S., Bhadra, U., Bhadra, M.P., Kalivendi, S.V., Rao, S.P., Row, A., Ibrahim, A., Ghosh, P.P., Mitra, P. Restoring mitochondrial function: A small molecule-mediated approach to enhance glucose stimulated insulin secretion in cholesterol accumulated pancreatic beta cells (2016) Scientific Reports, 6. DOI: 10.1038/srep27513
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Konda, S., Khatravath, M., Mallurwar, N.K., Rao, P., Sripelly, S., Iqbal, J., Arya, P. Stereoselective Synthesis of the C27-C35 Eribulin Fragment and Its Utilization in Building Structurally Diverse Macrocycles (2016) Synthesis (Germany), 48 (11), pp. 1663-1683. DOI: 10.1055/s-0035-1561431
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Rao, K.R., Raghunadh, A., Mekala, R., Meruva, S.B., Ganesh, K.R., Krishna, T., Kalita, D., Laxminarayana, E., Pal, M. Synthesis of Novel Drug-Like Small Molecules Based on Quinoxaline Containing Amino Substitution at C-2 (2016) Journal of Heterocyclic Chemistry, 53 (3), pp. 901-908. DOI: 10.1002/jhet.2177
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Shiva Kumar, K., Rajesham, B., Ramulu, M.S., Bhaskar, B., Dash, S.N., Ashfaq, M.A., Nagarapu, R., Khan, A.A., Lehtonen, S., Pal, M. Cu-Catalyzed ligand-free synthesis of rosuvastatin based novel indole derivatives as potential anticancer agents (2016) RSC Advances, 6 (102), pp. 100487-100493. DOI: 10.1039/c6ra20148b
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Jammula, S.R., Anna, V.R., Tatina, S., Krishna, T., Sreenivas, B.Y., Pal, M. A new strategy for accessing (S)-1-(furan-2-yl)pent-4-en-1-ol: a key precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins (2016) Tetrahedron Letters, 57 (35), pp. 3924-3928. DOI: 10.1016/j.tetlet.2016.07.059
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Kumar Reddy, D.N., Chandrasekhar, K.B., Siva Ganesh, Y.S., Reddy, G.R., Kumar, J.P., Kapavarapu, R.K., Pal, M. FeF3-catalyzed MCR in PEG-400: Ultrasound assisted synthesis of: N -substituted 2-aminopyridines (2016) RSC Advances, 6 (71), pp. 67212-67217. Cited 30 times. DOI: 10.1039/c6ra14228a
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Khubaib, M., Sheikh, J.A., Pandey, S., Srikanth, B., Bhuwan, M., Khan, N., Hasnain, S.E., Ehtesham, N.Z. Mycobacterium tuberculosis co-operonic PE32/PPE65 proteins alter host immune responses by hampering Th1 response (2016) Frontiers in Microbiology, 7 (MAY), art. no. 719. DOI: 10.3389/fmicb.2016.00719
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Kumar, K.S., Meesa, S.R., Rajesham, B., Bhasker, B., Ashfaq, M.A., Khan, A.A., Rao, S.S., Pal, M. AlCl3-mediated heteroarylation-cyclization strategy: One-pot synthesis of fused quinoxalines containing the central core of Lamellarin D (2016) RSC Advances, 6 (54), pp. 48324-48328. DOI: 10.1039/c6ra07507j
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Nikumbh, S.P., Raghunadh, A., Rao, T.S., Murthy, V.N., Joseph, S.C., Murthy, Y.L.N., Pal, M. A cascade reaction for the new and direct synthesis of indolofuroquinoxalines (2016) RSC Advances, 6 (28), pp. 23489-23497. DOI: 10.1039/c6ra03556f
2015
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Reddy, E.R., Yellanki, S., Medishetty, R., Konada, L., Alamuru, N.P., Haldar, D., Parsa, K.V.L., Kulkarni, P., Rajadurai, M. Red Fluorescent Organic Nanoparticle Bioprobes: A Photostable Cytoplasmic Stain for Long Term In Vitro and In Vivo Visualization (2015) ChemNanoMat, 1 (8), pp. 567-576. DOI: 10.1002/cnma.201500108
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Talari, M., Kapadia, B., Kain, V., Seshadri, S., Prajapati, B., Rajput, P., Misra, P., Parsa, K.V.L. MicroRNA-16 modulates macrophage polarization leading to improved insulin sensitivity in myoblasts (2015) Biochimie, 119, pp. 16-26. DOI: 10.1016/j.biochi.2015.10.004
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Jammula, S., Anna, V.R., Khobare, S.R., Kumar, U.K.S., Prasad, B., Pal, M. Dehydrative Annulation Strategy for the Construction of Octahydroindolizine Framework: A Diastereoselective Synthesis of (6 R,8a S)-Octahydroindolizin-6-ol (2015) Synthetic Communications, 45 (22), pp. 2576-2582. DOI: 10.1080/00397911.2015.1093146
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Kain, V., Kapadia, B., Viswakarma, N., Seshadri, S., Prajapati, B., Jena, P.K., Teja Meda, C.L., Subramanian, M., Kaimal Suraj, S., Kumar, S.T., Prakash Babu, P., Thimmapaya, B., Reddy, J.K., Parsa, K.V.L., Misra, P. Co-activator binding protein PIMT mediates TNF-α induced insulin resistance in skeletal muscle via the transcriptional down-regulation of MEF2A and GLUT4 (2015) Scientific Reports, 5. DOI: 10.1038/srep15197
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Kain, V., Kapadia, B., Misra, P., Saxena, U. Simvastatin may induce insulin resistance through a novel fatty acid mediated cholesterol independent mechanism (2015) Scientific Reports, 5. DOI: 10.1038/srep13823
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Nikumbh, S.P., Raghunadh, A., Murthy, V.N., Jinkala, R., Joseph, S.C., Murthy, Y.L.N., Prasad, B., Pal, M. A greener approach towards double heteroarylation of N, O and S nucleophiles: Synthesis of bioactive polynuclear fused N-heteroarenes (2015) RSC Advances, 5 (91), pp. 74570-74574. DOI: 10.1039/c5ra16727b
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Sunke, R., Kumar, V., Venkat Shivaji Ramarao, E.V., Bankala, R., Parsa, K.V.L., Pal, M. Quinoxaline: A new directing group for ortho C-H alkenylation / intramolecular ortho C-H cycloamination under open air leading to bioactive polynuclear N-heteroarenes (2015) RSC Advances, 5 (86), pp. 70604-70608. DOI: 10.1039/c5ra14671b
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Reddy, D.N.K., Chandrasekhar, K.B., Ganesh, Y.S.S., Sathish Kumar, B., Adepu, R., Pal, M. SnCl2·2H2O as a precatalyst in MCR: Synthesis of pyridine derivatives via a 4-component reaction in water (2015) Tetrahedron Letters, 56 (31), pp. 4586-4589. DOI: 10.1016/j.tetlet.2015.06.008
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Pasha, J., Kandagatla, B., Sen, S., Seerapu, G.P.K., Bujji, S., Haldar, D., Nanduri, S., Oruganti, S. Amberlyst-15 catalyzed Povarov reaction of N-arylidene-1H-indazol-6-amines and indoles: A greener approach to the synthesis of exo-1,6,7,7a,12,12a-hexahydroindolo[3,2-c]pyrazolo[3,4-f]quinolines as potential sirtuin inhibitors (2015) Tetrahedron Letters, 56 (18), pp. 2289-2292. DOI: 10.1016/j.tetlet.2015.03.078
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Bollikonda, S., Mohanarangam, S., Jinna, R.R., Kandirelli, V.K.K., Makthala, L., Sen, S., Chaplin, D.A., Lloyd, R.C., Mahoney, T., Dahanukar, V.H., Oruganti, S., Fox, M.E. An enantioselective formal synthesis of montelukast sodium (2015) Journal of Organic Chemistry, 80 (8), pp. 3891-3901. DOI: 10.1021/acs.joc.5b00197
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Dasari, B., Jimmidi, R., Arya, P. Selected hybrid natural products as tubulin modulators (2015) European Journal of Medicinal Chemistry, 94, pp. 497-508. DOI: 10.1016/j.ejmech.2014.10.062
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Reddy, D.N.K., Chandrasekhar, K.B., Ganesh, Y.S.S., Gorantla, S.S., Ramanjaneyulu, S., Kumar, K.S., Pal, M. PMA-SiO 2-Mediated MCR in PEG-400: A Greener aza-Friedel-Crafts Reaction Leading to 3-Arylmethyl/Diarylmethyl Indoles (2015) Synthetic Communications, 45 (4), pp. 513-523. DOI: 10.1080/00397911.2014.966392
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Jimmidi, R., Guduru, S.K.R., Arya, P. Practical stereoselective synthesis of eribulin fragment toward building a hybrid macrocyclic toolbox (2015) Organic Letters, 17 (3), pp. 468-471. DOI: 10.1021/ol503464s
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Aeluri, M., Dasari, B., Arya, P. Divergent approach to building a latrunculin family derived hybrid macrocyclic toolbox (2015) Organic Letters, 17 (3), pp. 472-475. DOI: 10.1021/ol503465p
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Guduru, S.K.R., Jimmidi, R., Deora, G.S., Arya, P. Stereoselective synthesis of rapamycin fragment to build a macrocyclic toolbox (2015) Organic Letters, 17 (3), pp. 480-483. DOI: 10.1021/ol5034833
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Prasad, B., Adepu, R., Sharma, A.K., Pal, M. Creation of molecular complexities via a new Cu-catalyzed cascade reaction: A direct access to novel 2,2′-spirobiindole derivatives (2015) Chemical Communications, 51 (7), pp. 1259-1262. DOI: 10.1039/c4cc08911a
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Rafi, S., Kandagatla, B., Darapaneni, B., Oruganti, S. Short & expedient synthesis of pyridine containing dihydrochalcone 1-(2-hydroxyphenyl)-3-(pyridin-4-yl)propan-1-one: A non-nutritive artificial sweetener (2015) Indian Journal of Heterocyclic Chemistry, 24 (4), pp. 459-464.
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Nallapati, S.B., Sreenivas, B.Y., Bankala, R., Parsa, K.V.L., Sripelly, S., Mukkanti, K., Pal, M. 1,2,3-Triazoles derived from olanzapine: Their synthesis via an ultrasound assisted CuAAC method and evaluation as inhibitors of PDE4B (2015) RSC Advances, 5 (115), pp. 94623-94628. DOI: 10.1039/c5ra20380e
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Nallapati, S.B., Adepu, R., Ashfaq, M.A., Sreenivas, B.Y., Mukkanti, K., Pal, M. A Pd-catalyzed direct entry to 11-substituted 6H-isoindolo[2,1-a]indol-6-one derivatives as potential anticancer agents (2015) RSC Advances, 5 (108), pp. 88686-88691. Cited 21 times. DOI: 10.1039/c5ra17908d
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Singh, S.N., Jayaprakash, S., Venkateshwara Reddy, K., Nakhi, A., Pal, M. A metal catalyst-free and one-pot synthesis of (3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methanol derivatives in water (2015) RSC Advances, 5 (103), pp. 84889-84893. DOI: 10.1039/c5ra14478g
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Prasad, B., Nallapati, S.B., Kolli, S.K., Sharma, A.K., Yellanki, S., Medisetti, R., Kulkarni, P., Sripelly, S., Mukkanti, K., Pal, M. Pd-catalyzed isocyanide insertion/nucleophilic attack by indole C-3/desulfonylation in the same pot: A direct access to indoloquinolines of pharmacological interest. DOI: 10.1039/c5ra13535d
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Rao, K.R., Mekala, R., Raghunadh, A., Meruva, S.B., Kumar, S.P., Kalita, D., Laxminarayana, E., Prasad, B., Pal, M. A catalyst-free rapid, practical and general synthesis of 2-substituted quinazolin-4(3H)-ones leading to luotonin B and E, bouchardatine and 8-norrutaecarpine (2015) RSC Advances, 5 (76), pp. 61575-61579. DOI: 10.1039/c5ra10928k
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Srinivas, P.T.V.A., Bhavani, S., Rambabu, D., Rao, M.V.B., Kapavarapu, R., Pal, M. FeCl3/ultrasound mediated reaction of 2-aminothiophenol with aldehydes in water: Synthesis of 2-substituted benzothiazoles of pharmacological interest (2015) Letters in Drug Design and Discovery, 12 (6), pp. 457-465. DOI: 10.2174/1570180812666141216211045
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Sunke, R., Kumar, V., Ashfaq, M.A., Yellanki, S., Medisetti, R., Kulkarni, P., Shivaji Ramarao, E.V.V., Ehtesham, N.Z., Pal, M. A Pd(II)-catalyzed C-H activation approach to densely functionalized N-heteroaromatics related to neocryptolepine and their evaluation as potential inducers of apoptosis (2015) RSC Advances, 5 (56), pp. 44722-44727. Cited 16 times. DOI: 10.1039/c5ra06764b
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Murthi, P.R., Suresh, N., Rani, C.S., Rao, M.V.B., Pal, M. Pd/C-catalyzed synthesis of (E)-2-arylmethylideneindolin-3-ols under ultrasound: Their initial evaluation as potential anti-proliferative agents (2015) Letters in Drug Design and Discovery, 12 (2), pp. 109-116. DOI: 10.2174/1570180811666140819224103
2014
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Kulkarni, P., Saxena, U. Investigational drugs for the management of Huntington’s disease: Are we there yet? (2014) Expert Opinion on Investigational Drugs, 23 (12), pp. 1595-1603. DOI: 10.1517/13543784.2014.934807
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Kolli, S.K., Nakhi, A., Archana, S., Saridena, M., Deora, G.S., Yellanki, S., Medisetti, R., Kulkarni, P., Ramesh Raju, R., Pal, M. Ligand-free Pd-catalyzed C-N cross-coupling/cyclization strategy: An unprecedented access to 1-thienyl pyrroloquinoxalines for the new approach towards apoptosis (2014) European Journal of Medicinal Chemistry, 86, pp. 270-278. DOI: 10.1016/j.ejmech.2014.08.057
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Rao, K.R., Raghunadh, A., Mekala, R., Meruva, S.B., Pratap, T.V., Krishna, T., Kalita, D., Laxminarayana, E., Prasad, B., Pal, M. Glyoxylic acid in the reaction of isatoic anhydride with amines: A rapid synthesis of 3-(un)substituted quinazolin-4(3H)-ones leading to rutaecarpine and evodiamine (2014) Tetrahedron Letters, 55 (43), pp. 6004-6006. DOI: 10.1016/j.tetlet.2014.09.011
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Gade, N.R., Iqbal, J. A Common Synthetic Protocol for the Cyclic and Acyclic Core of Migrastatin, Isomigrastatin, and Dorrigocin via a Chiral β-Hydroxy-γ-butyrolactone Intermediate (2014) European Journal of Organic Chemistry, 2014 (29), pp. 6558-6564. DOI: 10.1002/ejoc.201402830
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Sunke, R., Babu, P.V., Yellanki, S., Medishetti, R., Kulkarni, P., Pal, M. Ligand-free MCR for linking quinoxaline framework with a benzimidazole nucleus: A new strategy for the identification of novel hybrid molecules as potential inducers of apoptosis (2014) Organic and Biomolecular Chemistry, 12 (35), pp. 6800-6805. DOI: 10.1039/c4ob01268b
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Kolli, S.K., Nakhi, A., Medishetti, R., Yellanki, S., Kulkarni, P., Ramesh Raju, R., Pal, M. NaSH in the construction of thiophene ring fused with N-heterocycles: A rapid and inexpensive synthesis of novel small molecules as potential inducers of apoptosis (2014) Bioorganic and Medicinal Chemistry Letters, 24 (18), pp. 4460-4465 DOI: 10.1016/j.bmcl.2014.07.096
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Kolli, S.K., Prasad, B., Babu, P.V., Ashfaq, M.A., Ehtesham, N.Z., Raju, R.R., Pal, M. TFAA/H3PO4 mediated unprecedented N-acylation of carbazoles leading to small molecules possessing anti-proliferative activities against cancer cells (2014) Organic and Biomolecular Chemistry, 12 (32), pp. 6080-6084. DOI: 10.1039/c4ob00686k
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Naidu, P.P., Raghunadh, A., Rao, K.R., Mekala, R., Babu, J.M., Rao, B.R., Siddaiah, V., Pal, M. Urea/thiourea as ammonia surrogate: A catalyst-free synthesis of 2-substituted 2,3-dihydroquinazolin-4(1 H)-ones/quinazoline-4(3 H)-ones (2014) Synthetic Communications, 44 (10), pp. 1475-1482. DOI: 10.1080/00397911.2013.862551
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Dulla, B., Kolli, S.K., Chamakura, U.R., Deora, G.S., Raju, R.R., Pal, M. Pd/C-mediated arylation followed by I2-catalyzed hydration strategy: Preparation of functionalized novel indanone derivatives (2014) Synthetic Communications, 44 (10), pp. 1466-1474. DOI: 10.1080/00397911.2013.860554
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Aeluri, M., Chamakuri, S., Dasari, B., Guduru, S.K.R., Jimmidi, R., Jogula, S., Arya, P. Small molecule modulators of protein-protein interactions: Selected case studies (2014) Chemical Reviews, 114 (9), pp. 4640-4694. DOI: 10.1021/cr4004049
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Babu, P.V., Gorja, D.R., Meda, C.L.T., Deora, G.S., Kolli, S.K., Parsa, K.V.L., Mukkanti, K., Pal, M. Synthesis of N-(3-arylprop-2-ynyl) substituted olanzapine derivatives as potential inhibitors of PDE4B (2014) Tetrahedron Letters, 55 (20), pp. 3176-3180. DOI: 10.1016/j.tetlet.2014.04.009
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Prasad, B., Sreenivas, B.Y., Sushma, A., Yellanki, S., Medisetti, R., Kulkarni, P., Pal, M. A Pd-based regioselective strategy to indole-1,2-fused 8- and 9-membered rings: Their evaluation as potential scaffolds for apoptosis in zebrafish (2014) Organic and Biomolecular Chemistry, 12 (18), pp. 2864-2868. DOI: 10.1039/c4ob00140k
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Dulla, B., Tangellamudi, N.D., Balasubramanian, S., Yellanki, S., Medishetti, R., Kumar Banote, R., Hari Chaudhari, G., Kulkarni, P., Iqbal, J., Reiser, O., Pal, M. Isovanillin derived N-(un) substituted hydroxylamines possessing an ortho-allylic group: Valuable precursors to bioactive N-heterocycles (2014) Organic and Biomolecular Chemistry, 12 (16), pp. 2552-2558. DOI: 10.1039/c3ob42460j
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Adepu, R., Rajitha, A., Ahuja, D., Sharma, A.K., Ramudu, B., Kapavarapu, R., Parsa, K.V.L., Pal, M. A direct access to bioactive fused N-heterocyclic acetic acid derivatives (2014) Organic and Biomolecular Chemistry, 12 (16), pp. 2514-2518. DOI: 10.1039/c3ob42535e
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Rao, M.S., Haritha, M., Kolli, S.K., Basaveswara Rao, M.V., Pal, M. Catalysis by amberlyst A-21: A greener approach to 4,5,6,7-tetrahydro-1H- indazol-3(2H)-ones via construction of cyclohexanones (2014) Synthetic Communications, 44 (8), pp. 1076-1083. DOI: 10.1080/00397911.2013.844260
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Reddy Chamakura, U., Sailaja, E., Dulla, B., Kalle, A.M., Bhavani, S., Rambabu, D., Kapavarapu, R., Rao, M.V.B., Pal, M. Synthesis and in vitro anti-proliferative effects of 3-(hetero)aryl substituted 3-[(prop-2-ynyloxy)(thiophen-2-yl)methyl]pyridine derivatives on various cancer cell lines (2014) Bioorganic and Medicinal Chemistry Letters, 24 (5), pp. 1366-1372. DOI: 10.1016/j.bmcl.2014.01.044
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Rao, M.S., Haritha, M., Chandrasekhar, N., Basaveswara Rao, M.V., Pal, M. Pd/ligand-free synthesis of thienopyranones via Cu-catalyzed coupling-cyclization in PEG 400 under ultrasound (2014) Tetrahedron Letters, 55 (9), pp. 1660-1663. DOI: 10.1016/j.tetlet.2014.01.115
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Rao, R.M., Luther, B.J., Rani, C.S., Suresh, N., Kapavarapu, R., Parsa, K.V.L., Rao, M.V.B., Pal, M. Synthesis of 2H-1,3-benzoxazin-4(3H)-one derivatives containing indole moiety: Their in vitro evaluation against PDE4B (2014) Bioorganic and Medicinal Chemistry Letters, 24 (4), pp. 1166-1171. DOI: 10.1016/j.bmcl.2013.12.117
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Jimmidi, R., Shroff, G.K., Satyanarayana, M., Reddy, B.R., Kapireddy, J., Sawant, M.A., Sitaswad, S.L., Arya, P., Mitra, P. Prevention of mitochondrial membrane permeabilization and pancreatic β-cell death by an enantioenriched, macrocyclic small molecule (2014) European Journal of Organic Chemistry, 2014 (6), pp. 1151-1156. DOI: 10.1002/ejoc.201301769
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Rao, S.S., Rambabu, D., Layek, M., Kumar, K.L., Basaveswara Rao, M.V., Haldar, D., Pal, M. Cu-mediated synthesis of 2,3-dihydro-1h-pyrrolo[3,2,1-ij]quinolin-1-ones as potential inhibitors of sirtuins (2014) Letters in Drug Design and Discovery, 11 (2), pp. 199-206. DOI: 10.2174/15701808113109990065
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Dulla, B., Sailaja, E., Reddy Ch, U., Aeluri, M., Kalle, A.M., Bhavani, S., Rambabu, D., Rao, M.V.B., Pal, M. Synthesis of indole based novel small molecules and their in vitro anti-proliferative effects on various cancer cell lines (2014) Tetrahedron Letters, 55 (4), pp. 921-926. DOI: 10.1016/j.tetlet.2013.12.050
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Babu, P.V., Mukherjee, S., Gorja, D.R., Yellanki, S., Medisetti, R., Kulkarni, P., Mukkanti, K., Pal, M. Zebrafish based strategy for the identification of a potential pharmacophore for apoptosis: A greener CuAAC approach for novel 1,2,3-triazoles derived from mefenamic acid (2014) RSC Advances, 4 (10), pp. 4878-4882. DOI: 10.1039/c3ra46185h
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Radha Krishna Murthi, P., Rambabu, D., Basaveswara Rao, M.V., Pal, M. Synthesis of substituted pyrroles via Amberlyst-15 mediated MCR under ultrasound (2014) Tetrahedron Letters, 55 (2), pp. 507-509. DOI: 10.1016/j.tetlet.2013.11.073
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Vijayavardhini, S., Rambabu, D., Anuradha, V., Kapavarapu, R., Rao, M.V.B., Pal, M. Pd/C-mediated synthesis of 3-methyleneisoindolin-1-ones: Biological and theoretical study of their PDE4 inhibition (2014) Letters in Drug Design and Discovery, 11 (10), pp. 1188-1198. DOI: 10.2174/1570180811666140717190618
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Konda, S., Rao, P., Oruganti, S. Click chemistry route to tricyclic monosaccharide triazole hybrids: Design and synthesis of substituted hexahydro-4H-pyrano[2,3-f][1,2,3]triazolo[5,1-c][1,4]oxazepines (2014) RSC Advances, 4 (109), pp. 63962-63965. DOI: 10.1039/c4ra11035h
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Adepu, R., Prasad, B., Ashfaq, M.A., Ehtesham, N.Z., Pal, M. New MCR based on intramolecular Heck reaction under aerobic conditions: A direct access to cytotoxic fused N-heterocycles (2014) RSC Advances, 4 (90), pp. 49324-49328. DOI: 10.1039/c4ra10702k
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Botcha, A.K., Dulla, B., Reddy, E.R., Chennubhotla, K.S., Kulkarni, P., Chandrasekar, R., Rajadurai, M.S. Organic nanovesicular cargoes for sustained drug delivery: Synthesis, vesicle formation, controlling “pearling” states, and terfenadine loading/release studies (2014) Journal of Nanotechnology, 2014. DOI: 10.1155/2014/369139
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Singh, S.N., Bopanni, R., Jayaprakash, S., Reddy, K.V., Ashfaq, M.A., Kumar, K.S., Pal, M. Reactions of salicylaldehydes with activated terminal alkynes in aqueous media: Synthesis of 3-substituted 4-hydroxy chromenes as potential cytotoxic agents (2014) RSC Advances, 4 (47), pp. 24870-24873. DOI: 10.1039/c4ra03882g
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Alamuru, N.P., Behera, S., Butchar, J.P., Tridandapani, S., Kaimal Suraj, S., Prakash Babu, P., Hasnain, S.E., Ehtesham, N.Z., Parsa, K.V.L. A novel immunomodulatory function of PHLPP1: Inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages (2014) Journal of Leukocyte Biology, 95 (5), pp. 775-783. DOI: 10.1189/jlb.0713360
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Kulkarni, P., Chaudhari, G.H., Sripuram, V., Banote, R.K., Kirla, K.T., Sultana, R., Rao, P., Oruganti, S., Chatti, K. Oral dosing in adult zebrafish: Proof-of-concept using pharmacokinetics and pharmacological evaluation of carbamazepine (2014) Pharmacological Reports, 66 (1), pp. 179-183. DOI: 10.1016/j.pharep.2013.06.012
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Reddy, S.V., Rao, G.M., Kumar, B.V., Reddy, K.N., Sravya, K., Goverdhan, P., Rathore, V., Deora, G.S., Pal, M. Construction of phenoxazine rings containing nitro and sulfonic acid groups leading to phenoxazine-3-sulfonamide derivatives: Their evaluation as novel and potential insulin secretagogues (2014) Medicinal Chemistry Communications, 5 (5), pp. 587-592. DOI: 10.1039/c3md00377a
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Kulkarni, P., Saxena, Head and neck cancers, the neglected malignancies: Present and future treatment strategies (2014) Expert Opinion on Therapeutic Targets, 18 (4), pp. 351-354. DOI: 10.1517/14728222.2014.888059
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Chary, R.G., Reddy, G.R., Ganesh, Y.S.S., Prasad, K.V., Raghunadh, A., Krishna, T., Mukherjee, S., Pal, M. Effect of aqueous polyethylene glycol on 1,3-dipolar cycloaddition of benzoylnitromethane/ethyl 2-nitroacetate with dipolarophiles: Green synthesis of isoxazoles and isoxazolines (2014) Advanced Synthesis and Catalysis, 356 (1), pp. 160 DOI: 10.1002/adsc.201300712
2013
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Kumar, S.K., Rambabu, D., Kumar, C.H.V., Sreenivas, B.Y., Prasad, K.R.S., Rao, M.V.B., Pal, M. Catalysis by Amberlyst-15 under ultrasound in water: A green synthesis of 1,2,4-benzothiadiazine-1,1-dioxides and their spiro derivatives (2013) RSC Advances, 3 (47), pp. 24863-24867. DOI: 10.1039/c3ra44703k
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Kapadia, B., Viswakarma, N., Parsa, K.V.L., Kain, V., Behera, S., Suraj, S.K., Prakash Babu, P., Kar, A., Panda, S., Zhu, Y.-J., Jia, Y., Thimmapaya, B., Reddy, J.K., Misra, P.ERK2-mediated phosphorylation of transcriptional coactivator binding protein PIMT/NCoA6IP at Ser298 augments hepatic gluconeogenesis (2013) PLOS ONE, 8 (12). DOI: 10.1371/journal.pone.0083787
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Suragania, M., Aadinarayana, V.D., Pinjaria, A.B., Tanneerub, K., Guruprasadb, L., Banerjeec, S., Pandeya, S., Chaudhurid, T.K., Ehteshama, N.Z. Human resistin, a proinflammatory cytokine, shows chaperone-like activity (2013) Proceedings of the National Academy of Sciences of the United States of America, 110 (51), pp. 20467-20472. DOI: 10.1073/pnas.1306145110
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Reddy, G.R., Reddy, T.R., Chary, R.G., Joseph, S.C., Mukherjee, S., Pal, M. β-Cyclodextrin mediated MCR in water: Synthesis of dihydroisoindolo[2,1-a]quinazoline-5,11-dione derivatives under microwave irradiation (2013) Tetrahedron Letters, 54 (49), pp. 6744-6746. DOI: 10.1016/j.tetlet.2013.09.138
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Rambabu, D., Murthi, P.R.K., Dulla, B., Basaveswara Rao, M.V., Pal, M. Amberlyst-15-catalyzed synthesis of 2-substituted 1,3-benzazoles in water under ultrasound (2013) Synthetic Communications, 43 (22), pp. 3083-3092. DOI: 10.1080/00397911.2013.769605
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Mukherjee, S., Pal, M. Medicinal chemistry of quinolines as emerging anti-inflammatory agents: An overview (2013) Current Medicinal Chemistry, 20 (35), pp. 4386-4410. DOI: 10.2174/09298673113209990170
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Babu, P.V., Mukherjee, S., Deora, G.S., Chennubhotla, K.S., Medisetti, R., Yellanki, S., Kulkarni, P., Sripelly, S., Parsa, K.V.L., Chatti, K., Mukkanti, K., Pal, M. Ligand/PTC-free intramolecular Heck reaction: Synthesis of pyrroloquinoxalines and their evaluation against PDE4/luciferase/oral cancer cell growth in vitro and zebrafish in vivo (2013) Organic and Biomolecular Chemistry, 11 (39), pp. 6680-6685. DOI: 10.1039/c3ob41504j
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Singh, S.N., Regati, S., Paul, A.K., Layek, M., Jayaprakash, S., Reddy, K.V., Deora, G.S., Mukherjee, S., Pal, M. Cu-mediated 1,3-dipolar cycloaddition of azomethine ylides with dipolarophiles: A faster access to spirooxindoles of potential pharmacological interest (2013) Tetrahedron Letters, 54 (40), pp. 5448-5452. DOI: 10.1016/j.tetlet.2013.07.126
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Challa, A.K., Chatti, K. Conservation and early expression of zebrafish tyrosine kinases support the utility of zebrafish as a model for tyrosine kinase biology (2013) Zebrafish, 10 (3), pp. 264-274. DOI: 10.1089/zeb.2012.0781
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Nakhi, A., Rahman, M.S., Seerapu, G.P.K., Banote, R.K., Kumar, K.L., Kulkarni, P., Haldar, D., Pal, M. Transition metal free hydrolysis/cyclization strategy in a single pot: Synthesis of fused furo N-heterocycles of pharmacological interest (2013) Organic and Biomolecular Chemistry, 11 (30), pp. 4930-4934. DOI: 10.1039/c3ob41069b
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Gade, N.R., Iqbal, J. Stereoselective formal synthesis of macrolidecore of migrastatin using late stage C-H oxidation (2013) Tetrahedron Letters, 54 (32), pp. 4225-4227. DOI: 10.1016/j.tetlet.2013.05.137
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Kuna, R.S., Girada, S.B., Asalla, S., Vallentyne, J., Maddika, S., Patterson, J.T., Smiley, D.L., DiMarchi, R.D., Mitra, P. Glucagon-like peptide-1 receptor-mediated endosomal cAMP generation promotes glucose-stimulated insulin secretion in pancreatic β-cells (2013) American Journal of Physiology – Endocrinology and Metabolism, 305 (2), pp. E161-E170. DOI: 10.1152/ajpendo.00551.2012
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Nakhi, A., Shafiqur Rahman, M., Archana, S., Kishore, R., Seerapu, G.P.K., Lalith Kumar, K., Haldar, D., Pal, M. Construction and functionalization of pyranone ring fused with pyran moiety: Design and synthesis of novel pyrano[4,3-b]pyran-5(4H)-ones as potential inhibitors of sirtuins (2013) Bioorganic and Medicinal Chemistry Letters, 23 (14), pp. 4195-4205. DOI: 10.1016/j.bmcl.2013.05.014
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Reddy Guduru, S.K., Chamakuri, S., Chandrasekar, G., Kitambi, S.S., Arya, P. Tetrahydroquinoline-derived macrocyclic toolbox: The discovery of antiangiogenesis agents in zebrafish assay (2013) ACS Medicinal Chemistry Letters, 4 (7), pp. 666-670. DOI: 10.1021/ml400026n
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Jogula, S., Dasari, B., Khatravath, M., Chandrasekar, G., Kitambi, S.S., Arya, P. Building a macrocyclic toolbox from C-linked carbohydrates identifies antiangiogenesis agents from zebrafish assay (2013) European Journal of Organic Chemistry, (23), pp. 5036-5040. DOI: 10.1002/ejoc.201300548
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Kandagatla, B., Prasada Raju, V.V.N.K.V., Kumar, N.S., Reddy, G.M., Srinivas, K., Iqbal, J., Bandichhor, R., Oruganti, S. Practical synthesis of fingolimod from diethyl acetamidomalonate (2013) RSC Advances, 3 (25), pp. 9687-9689. Cited 8 times. DOI: 10.1039/c3ra40894a
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Chary, R.G., Reddy, G.R., Ganesh, Y.S.S., Prasad, K.V., Chandra, S.K.P., Mukherjee, S., Pal, M. Cu-catalyzed coupling-cyclization in PEG 400 under ultrasound: A highly selective and greener approach towards isocoumarins (2013) RSC Advances, 3 (25), pp. 9641-9644. Cited 35 times. DOI: 10.1039/c3ra40969d
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Aeluri, M., Gaddam, J., Trinath, D.V.K.S., Chandrasekar, G., Kitambi, S.S., Arya, P. An intramolecular heck approach to obtain 17-membered macrocyclic diversity and the identification of an antiangiogenesis agent from a zebrafish assay (2013) European Journal of Organic Chemistry, (19), pp. 3955-3958. DOI: 10.1002/ejoc.201300408
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Chamakuri, S., Guduru, S.K.R., Pamu, S., Chandrasekar, G., Kitambi, S.S., Arya, P. A modular approach to build macrocyclic diversity in aminoindoline scaffolds identifies antiangiogenesis agents from a zebrafish assay (2013) European Journal of Organic Chemistry, (19), pp. 3959-3964. DOI: 10.1002/ejoc.201300409
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Rambabu, D., Kumar, G.P., Kumar, B.D., Kapavarapu, R., Rao, M.V.B., Pal, M. Pd/C-mediated synthesis of (Z)-3-alkylidenephthalides of potential pharmacological interest (2013) Tetrahedron Letters, 54 (23), pp. 2989-2995. DOI: 10.1016/j.tetlet.2013.03.121
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Dulla, B., Kirla, K.T., Rathore, V., Deora, G.S., Kavela, S., Maddika, S., Chatti, K., Reiser, O., Iqbal, J., Pal, M. Synthesis and evaluation of 3-amino/guanidine substituted phenyl oxazoles as a novel class of LSD1 inhibitors with anti-proliferative properties (2013) Organic and Biomolecular Chemistry, 11 (19), pp. 3103-3107. DOI: 10.1039/c3ob40217g
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Rapolu, R.K., Nabamukul, B., Bommineni, S.R., Potham, R., Mulakayala, N., Oruganti, S. Silica sulfuric acid: A reusable solid catalyst for the synthesis of N-substituted amides via the Ritter reaction (2013) RSC Advances, 3 (16), pp. 5332-5337. Cited 17 times. DOI: 10.1039/c3ra23157g
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Rambabu, D., Bhavani, S., Nalivela, K.S., Mukherjee, S., Rao, M.V.B., Pal, M. Pd/C-Cu mediated direct and one-pot synthesis of γ-ylidene butenolides (2013) Tetrahedron Letters, 54 (17), pp. 2151-2155. DOI: 10.1016/j.tetlet.2013.02.040
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Nakhi, A., Srinivas, P.T.V.A., Rahman, M.S., Kishore, R., Seerapu, G.P.K., Lalith Kumar, K., Haldar, D., Rao, M.V.B., Pal, M. Amberlite IR-120H catalyzed MCR: Design, synthesis and crystal structure analysis of 1,8-dioxodecahydroacridines as potential inhibitors of sirtuins (2013) Bioorganic and Medicinal Chemistry Letters, 23 (6), pp. 1828-1833.
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Chaudhari, G.H., Chennubhotla, K.S., Chatti, K., Kulkarni, P. Optimization of the adult zebrafish ECG method for assessment of drug-induced QTc prolongation (2013) Journal of Pharmacological and Toxicological Methods, 67 (2), pp. 115-120. Cited 37 times. DOI: 10.1016/j.vascn.2013.01.007
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Rambabu, D., Bhavani, S., Swamy, N.K., Basaveswara Rao, M.V., Pal, M. Pd/C-mediated depropargylation of propargyl ethers/amines in water (2013) Tetrahedron Letters, 54 (9), pp. 1169-1173. DOI: 10.1016/j.tetlet.2012.12.093
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Rambabu, D., Kiran Kumar, S., Yogi Sreenivas, B., Sandra, S., Kandale, A., Misra, P., Basaveswara Rao, M.V., Pal, M. Ultrasound-based approach to spiro-2,3-dihydroquinazolin-4(1H)-ones: Their in vitro evaluation against chorismate mutase (2013) Tetrahedron Letters, 54 (6), pp. 495-501. DOI: 10.1016/j.tetlet.2012.11.057
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Aeluri, M., Pramanik, C., Chetia, L., Mallurwar, N.K., Balasubramanian, S., Chandrasekar, G., Kitambi, S.S., Arya, P. 14-membered macrocyclic ring-derived toolbox: The identification of small molecule inhibitors of angiogenesis and early embryo development in zebrafish assay (2013) Organic Letters, 15 (3), pp. 436-439. DOI: 10.1021/ol3032126
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Dasari, B., Jogula, S., Borhade, R., Balasubramanian, S., Chandrasekar, G., Kitambi, S.S., Arya, P. Macrocyclic glycohybrid toolbox identifies novel antiangiogenesis agents from zebrafish assay (2013) Organic Letters, 15 (3), pp. 432-435. DOI: 10.1021/ol3032297
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Mallikarjuna Rao, V., Mahesh Kumar, P., Rambabu, D., Kapavarapu, R., Shobha Rani, S., Misra, P., Pal, M. Novel alkynyl substituted 3,4-dihydropyrimidin-2(1H)-one derivatives as potential inhibitors of chorismate mutase (2013) Bioorganic Chemistry, 51, pp. 48-53. DOI: 10.1016/j.bioorg.2013.08.002
2012
- Kandagatla, B., Raju, V.V.N.K.V.P., Reddy, G.M., Rao, S.C., Iqbal, J., Bandichhor, R., Oruganti, S. A facile synthesis of melatonergic antidepressant agomelatine (2012) Tetrahedron Letters, 53 (52), pp. 7125-7127. DOI: 10.1016/j.tetlet.2012.10.07
- Reddy, G.R., Reddy, T.R., Joseph, S.C., Reddy, K.S., Meda, C.L.T., Kandale, A., Rambabu, D., Krishna, G.R., Reddy, C.M., Parsa, K.V.L., Kumar, K.S., Pal, M. Yb(OTf)3 mediated MCR: A new and regioselective approach towards polysubstituted pyrroles of pharmacological interest (2012) RSC Advances, 2 (24), pp. 9142-9150. DOI: 10.1039/c2ra21343e
- Mulakayala, N., Pavan Kumar, G., Rambabu, D., Aeluri, M., Basaveswara Rao, M.V., Pal, M. A greener synthesis of 1,8-dioxo-octahydroxanthene derivatives under ultrasound (2012) Tetrahedron Letters, 53 (51), pp. 6923-6926. DOI: 10.1016/j.tetlet.2012.10.024
- Mahesh Kumar, P., Siva Kumar, K., Kumar Mohakhud, P., Mukkanti, K., Kapavarapu, R., Parsa, K.V.L., Manojit, P.P. Construction of a six-membered fused N-heterocyclic ring via a new 3-component reaction: Synthesis of (pyrazolo)pyrimidines/pyridines (2012) Chemical Communications, 48 (3), pp. 431-433. DOI: 10.1039/c1cc16418j
- Bhaskar Kumar, T., Sumanth, C., Dhanunjaya Rao, A.V., Kalita, D., Srinivasa Rao, M., Chandra Sekhar, K.B., Shiva Kumar, K., Pal, M. Catalysis by FeF 3 in water: A green synthesis of 2-substituted 1,3-benzazoles and 1,2-disubstituted benzimidazoles (2012) RSC Advances, 2 (30), pp. 11510-11519. DOI: 10.1039/c2ra22302c
- Rambabu, D., Murthy, P.V.N.S., Prasad, K.R.S., Kandale, A., Deora, G.S., Basaveswara Rao, M.V., Pal, M. AgNO 3 mediated C-N bond forming reaction: Synthesis of 3-substituted benzothiazines as potential COX inhibitors (2012) Tetrahedron Letters, 53 (48), pp. 6577-6583. DOI: 10.1016/j.tetlet.2012.09.102
- Mulakayala, N., Ismail, Kumar, K.M., Rapolu, R.K., Kandagatla, B., Rao, P., Oruganti, S., Pal, M. Catalysis by Amberlite IR-120 resin: A rapid and green method for the synthesis of phenols from arylboronic acids under metal, ligand, and base-free conditions (2012) Tetrahedron Letters, 53 (45), pp. 6004-6007. DOI: 10.1016/j.tetlet.2012.08.087
- Prasad, B., Shiva Kumar, K., Vijaya Babu, P., Anusha, K., Rambabu, D., Kandale, A., Vanaja, G.R., Kalle, A.M., Pal, M. AlCl 3 induced C-N bond formation followed by Pd/C-Cu mediated coupling-cyclization strategy: Synthesis of pyrrolo[2,3-b]quinoxalines as anticancer agents (2012) Tetrahedron Letters, 53 (45), pp. 6059-6066. DOI: 10.1016/j.tetlet.2012.08.119
- Rambabu, D., Mulakayala, N., Ismail, Ravi Kumar, K., Pavan Kumar, G., Mulakayala, C., Kumar, C.S., Kalle, A.M., Basaveswara Rao, M.V., Oruganti, S., Pal, M. Synthesis and pharmacological evaluation of N-substituted 2-(2-oxo-2H-chromen-4-yloxy)propanamide as cyclooxygenase inhibitors (2012) Bioorganic and Medicinal Chemistry Letters, 22 (21), pp. 6745-6749. DOI: 10.1016/j.bmcl.2012.08.082
- Nakhi, A., Rahman, M.S., Kishore, R., Meda, C.L.T., Deora, G.S., Parsa, K.V.L., Pal, M. Pyrrolo[2,3-b]quinoxalines as inhibitors of firefly luciferase: Their Cu-mediated synthesis and evaluation as false positives in a reporter gene assay (2012) Bioorganic and Medicinal Chemistry Letters, 22 (20), pp. 6433-6441. DOI: 10.1016/j.bmcl.2012.08.056
- Manjulatha, K., Srinivas, S., Mulakayala, N., Rambabu, D., Prabhakar, M., Arunasree, K.M., Alvala, M., Basaveswara Rao, M.V., Pal, M. Ethylenediamine diacetate (EDDA) mediated synthesis of aurones under ultrasound: Their evaluation as inhibitors of SIRT1 (2012) Bioorganic and Medicinal Chemistry Letters, 22 (19), pp. 6160-6165. DOI: 10.1016/j.bmcl.2012.08.017
- Prasad, B., Adepu, R., Sandra, S., Rambabu, D., Krishna, G.R., Reddy, C.M., Deora, G.S., Misra, P., Pal, M. AlCl3 mediated unexpected migration of sulfonyl groups: Regioselective synthesis of 7-sulfonyl indoles of potential pharmacological interest (2012) Chemical Communications, 48 (84), pp. 10434-10436. DOI: 10.1039/c2cc35757g
- Rao, P., Konda, S., Iqbal, J., Oruganti, S. InCl 3 catalyzed three-component synthesis of α-benzylamino coumarins and diketones (2012) Tetrahedron Letters, 53 (39), pp. 5314-5317. DOI: 10.1016/j.tetlet.2012.07.098
- Reddy, E.R., Banote, R.K., Chatti, K., Kulkarni, P., Rajadurai, M.S. Selective Multicolour Imaging of Zebrafish Muscle Fibres by Using Fluorescent Organic Nanoparticles (2012) ChemBioChem, 13 (13), pp. 1889-1894. DOI: 10.1002/cbic.201200350
- Bhaskar Kumar, T., Sumanth, C., Vaishaly, S., Srinivasa Rao, M., Chandra Sekhar, K.B., Meda, C.L.T., Kandale, A., Rambabu, D., Rama Krishna, G., Malla Reddy, C., Shiva Kumar, K., Parsa, K.V.L., Pal, M. Pd-mediated functionalization of polysubstituted pyrroles: Their evaluation as potential inhibitors of PDE4 (2012) Bioorganic and Medicinal Chemistry Letters, 22 (17), pp. 5639-5647. DOI: 10.1016/j.bmcl.2012.06.100
- Adepu, R., Shiva Kumar, K., Sandra, S., Rambabu, D., Rama Krishna, G., Malla Reddy, C., Kandale, A., Misra, P., Pal, M. C-N bond formation under Cu-catalysis: Synthesis and in vitro evaluation of N-aryl substituted thieno[2,3-d] pyrimidin-4(3H)-ones against chorismate mutase (2012) Bioorganic and Medicinal Chemistry, 20 (17), pp. 5127-5138. DOI: 10.1016/j.bmc.2012.07.011
- Adepu, R., Rambabu, D., Prasad, B., Meda, C.L.T., Kandale, A., Rama Krishna, G., Malla Reddy, C., Chennuru, L.N., Parsa, K.V.L., Pal, M. Novel thieno[2,3-d] pyrimidines: Their design, synthesis, crystal structure analysis and pharmacological evaluation (2012) Organic and Biomolecular Chemistry, 10 (29), pp. 5554-5569. DOI: 10.1039/c2ob25420d
- Mulakayala, N., Kandagatla, B., Ismail, Rapolu, R.K., Rao, P., Mulakayala, C., Kumar, C.S., Iqbal, J., Oruganti, S. InCl 3-catalysed synthesis of 2-aryl quinazolin-4(3H)-ones and 5-aryl pyrazolo[4,3-d] pyrimidin-7(6H)-ones and their evaluation as potential anticancer agents (2012) Bioorganic and Medicinal Chemistry Letters, 22 (15), pp. 5063-5066. DOI: 10.1016/j.bmcl.2012.06.003
- Arunkumar, K., Naresh Kumar Reddy, D., Chandrasekhar, K.B., Rajender Kumar, P., Shiva Kumar, K., Pal, M. Catalysis by zeolite leading to the construction of thiazole ring: An improved synthesis of 4-alkynyl substituted thiazoles (2012) Tetrahedron Letters, 53 (30), pp. 3885-3889. DOI: 10.1016/j.tetlet.2012.05.062
- Dulla, B., Wan, B., Franzblau, S.G., Kapavarapu, R., Reiser, O., Iqbal, J., Pal, M. Construction and functionalization of fused pyridine ring leading to novel compounds as potential antitubercular agents (2012) Bioorganic and Medicinal Chemistry Letters, 22 (14), pp. 4629-4635. DOI: 10.1016/j.bmcl.2012.05.096
- Nakhi, A., Adepu, R., Rambabu, D., Kishore, R., Vanaja, G.R., Kalle, A.M., Pal, M. Thieno[3,2-c] pyran-4-one based novel small molecules: Their synthesis, crystal structure analysis and in vitro evaluation as potential anticancer agents (2012) Bioorganic and Medicinal Chemistry Letters, 22 (13), pp. 4418-4427. DOI: 10.1016/j.bmcl.2012.04.109
- Shiva Kumar, K., Rambabu, D., Prasad, B., Mujahid, M., Krishna, G.R., Basaveswara Rao, M.V., Malla Reddy, C., Vanaja, G.R., Kalle, A.M., Pal, M. A new approach to construct a fused 2-ylidene chromene ring: Highly regioselective synthesis of novel chromeno quinoxalines (2012) Organic and Biomolecular Chemistry, 10 (24), pp. 4774-4781. DOI: 10.1039/c2ob25416f
- Rambabu, D., Rama Krishna, G., Basavoju, S., Basaveswara Rao, M.V., Malla Reddy, C., Pal, M. Synthesis and crystal structure analysis of substituted 2-(3-(hydroxymethyl) quinolin-2-yl) phenol derivatives (2012) Journal of Molecular Structure, 1016, pp. 126-133. DOI: 10.1016/j.molstruc.2012.02.054
- Ellanki, A.R., Islam, A., Rama, V.S., Pulipati, R.P., Rambabu, D., Rama Krishna, G., Malla Reddy, C., Mukkanti, K., Vanaja, G.R., Kalle, A.M., Shiva Kumar, K., Pal, M. Solvent effect on copper-catalyzed azide-alkyne cycloaddition (CuAAC): Synthesis of novel triazolyl substituted quinolines as potential anticancer agents (2012) Bioorganic and Medicinal Chemistry Letters, 22 (10), pp. 3455-3459. DOI: 10.1016/j.bmcl.2012.03.091
- Shyamsunder Reddy, T., Shiva Kumar, K., Meda, C.L.T., Kandale, A., Rambabu, D., Rama Krishna, G., Hariprasad, C., Venugopala Rao, V., Venkataiah, S., Malla Reddy, C., Naidu, A., Dubey, P.K., Parsa, K.V.L., Pal, M. Conformationally restricted novel pyrazole derivatives: Synthesis of 1,8-disubstituted 5,5-dimethyl-4,5-dihydro-1H-benzo[g] indazoles as a new class of PDE4 inhibitors (2012) Bioorganic and Medicinal Chemistry Letters, 22 (9), pp. 3248-3255. DOI: 10.1016/j.bmcl.2012.03.029
- Reddy, G.R., Reddy, T.R., Joseph, S.C., Reddy, K.S., Pal, M. Iodine catalyzed four-component reaction: A straightforward one-pot synthesis of functionalized pyrroles under metal-free conditions (2012) RSC Advances, 2 (8), pp. 3387-3395. DOI: 10.1039/c2ra00982j
- Siva Kumar, K., Mahesh Kumar, P., Sreenivasa Rao, V., Jafar, A.A., Meda, C.L.T., Kapavarapu, R., Parsa, K.V.L., Pal, M. A new cascade reaction: Concurrent construction of six and five membered rings leading to novel fused quinazolinones (2012) Organic and Biomolecular Chemistry, 10 (15), pp. 3098-3103. DOI: 10.1039/c2ob25296a
- Gorja, D.R., Shiva Kumar, K., Kandale, A., Meda, C.L.T., Parsa, K.V.L., Mukkanti, K., Pal, M. Design and synthesis of 4-alkynyl pyrazoles as inhibitors of PDE4: A practical access via Pd/C-Cu catalysis (2012) Bioorganic and Medicinal Chemistry Letters, 22 (7), pp. 2480-2487. DOI: 10.1016/j.bmcl.2012.02.008
- Kumar, K.S., Kiran Kumar, S., Yogi Sreenivas, B., Gorja, D.R., Kapavarapu, R., Rambabu, D., Rama Krishna, G., Reddy, C.M., Basaveswara Rao, M.V., Parsa, K.V.L., Pal, M. C-C bond formation at C-2 of a quinoline ring: Synthesis of 2-(1H-indol-3-yl) quinoline-3-carbonitrile derivatives as a new class of PDE4 inhibitors (2012) Bioorganic and Medicinal Chemistry, 20 (7), pp. 2199-2207. DOI: 10.1016/j.bmc.2012.02.027
- Mulakayala, N., Murthy, P.V.N.S., Rambabu, D., Aeluri, M., Adepu, R., Krishna, G.R., Reddy, C.M., Prasad, K.R.S., Chaitanya, M., Kumar, C.S., Basaveswara Rao, M.V., Pal, M. Catalysis by molecular iodine: A rapid synthesis of 1,8-dioxo- octahydroxanthenes and their evaluation as potential anticancer agents (2012) Bioorganic and Medicinal Chemistry Letters, 22 (6), pp. 2186-2191. DOI: 10.1016/j.bmcl.2012.01.126
- Kumar, K.S., Rambabu, D., Sandra, S., Kapavarapu, R., Krishna, G.R., Basaveswara Rao, M.V., Chatti, K., Reddy, C.M., Misra, P., Pal, M. AlCl 3 induced (hetero)arylation of 2,3-dichloroquinoxaline: A one-pot synthesis of mono/disubstituted quinoxalines as potential antitubercular agents (2012) Bioorganic and Medicinal Chemistry, 20 (5), pp. 1711-1722. DOI: 10.1016/j.bmc.2012.01.012
- Kumar, K.S., Adepu, R., Kapavarapu, R., Rambabu, D., Krishna, G.R., Reddy, C.M., Priya, K.K., Parsa, K.V.L., Pal, M. AlCl 3 induced C-arylation/cyclization in a single pot: A new route to benzofuran fused N-heterocycles of pharmacological interest (2012) Tetrahedron Letters, 53 (9), pp. 1134-1138. DOI: 10.1016/j.tetlet.2011.12.096
- Sreenivasulu, M., Kumar, K.S., Kumar, P.R., Chandrasekhar, K.B., Pal, M. N-heterocyclic carbene-mediated hydroacylation-Sonogashira/Heck/Suzuki coupling in a single pot: A new cascade reaction (2012) Organic and Biomolecular Chemistry, 10 (8), pp. 1670-1679. DOI: 10.1039/c2ob06950d
- Vns Murthy, P., Rambabu, D., Rama Krishna, G., Malla Reddy, C., Prasad, K.R.S., Basaveswara Rao, M.V., Pal, M. Amberlyst-15 mediated synthesis of 2-substituted 2,3-dihydroquinazolin- 4(1H)-ones and their crystal structure analysis (2012) Tetrahedron Letters, 53 (7), pp. 863-867. DOI: 10.1016/j.tetlet.2011.12.023
- Ram Reddy, T., Rajeshwar Reddy, G., Srinivasula Reddy, L., Jammula, S., Lingappa, Y., Kapavarapu, R., Meda, C.L.T., Parsa, K.V.L., Pal, M. Montmorillonite K-10 mediated green synthesis of cyano pyridines: Their evaluation as potential inhibitors of PDE4 (2012) European Journal of Medicinal Chemistry, 48, pp. 265-274. DOI: 10.1016/j.ejmech.2011.12.024
- Iqbal, J., Tangellamudi, N.D., Dulla, B., Balasubramanian, S. Sequential C-N and C-O bond formation in a single pot: Synthesis of 2 H –benzo [ b ][1,4] oxazines from 2,5-dihydroxybenzaldehyde and amino acid precursors (2012) Organic Letters, 14 (2), pp. 552-555. DOI: 10.1021/ol2031747
- Mulakayala, N., Rambabu, D., Raja, M.R., Chaitanya, M.C., Kumar, C.S., Kalle, A.M., Rama Krishna, G., Malla Reddy, C., Basaveswara Rao, M.V., Pal, M. Ultrasound mediated catalyst free synthesis of 6H-1-benzopyrano[4,3-b] quinolin-6-ones leading to novel quinoline derivatives: Their evaluation as potential anti-cancer agents (2012) Bioorganic and Medicinal Chemistry, 20 (2), pp. 759-768. DOI: 10.1016/j.bmc.2011.12.001
- Shiva Kumar, K., Adepu, R., Sandra, S., Rambabu, D., Rama Krishna, G., Malla Reddy, C., Misra, P., Pal, M. Cu-mediated N-arylation of 1,2,3-triazin-4-ones: Synthesis of fused triazinone derivatives as potential inhibitors of chorismate mutase (2012) Bioorganic and Medicinal Chemistry Letters, 22 (2), pp. 1146-1150. DOI: 10.1016/j.bmcl.2011.11.096
- Kumar, P.M., Kumar, K.S., Meda, C.L.T., Reddy, G.R., Mohakhud, P.K., Mukkanti, K., Krishna, G.R., Reddy, C.M., Rambabu, D., Kumar, K.S., Priya, K.K., Chennubhotla, K.S., Banote, R.K., Kulkarni, P., Parsa, K.V.L., Pal, M. (Pd/C-mediated) coupling-iodocyclization-coupling strategy in discovery of novel PDE4 inhibitors: A new synthesis of pyrazolopyrimidines (2012) MedChemComm, 3 (6), pp. 667-672. DOI: 10.1039/c2md00273f
- Reddy, T.R., Reddy, L.S., Reddy, G.R., Yarbagi, K., Lingappa, Y., Rambabu, D., Krishna, G.R., Reddy, C.M., Kumar, K.S., Pal, M. Construction of a quinoline ring via a 3-component reaction in water: Crystal structure analysis and H-bonding patterns of a 2-aryl quinolone (2012) Green Chemistry, 14 (7), pp. 1870-1872. DOI: 10.1039/c2gc35256g
2011
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Pal, S., Durgadas, S., Nallapati, S.B., Mukkanti, K., Kapavarapu, R., Meda, C.L.T., Meda, K.V.L., Pal, M. Novel 1-alkynyl substituted 1,2-dihydroquinoline derivatives from nimesulide (and their 2-oxo analogues): A new strategy to identify inhibitors of PDE4B (2011) Bioorganic and Medicinal Chemistry Letters, 21 (21), pp. 6573-6576. DOI: 10.1016/j.bmcl.2011.08.033
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Reddy, T.R., Reddy, L.S., Reddy, R., Nuthalapati, V.S., Lingappa, Y., Sandra, S., Kapavarapu, R., Misra, P., Pal, M. A pd-mediated new strategy to functionalized 2-aminochromenes: Their in vitro evaluation as potential anti tuberculosis agents (2011) Bioorganic and Medicinal Chemistry Letters, 21 (21), pp. 6433-6439. DOI: 10.1016/j.bmcl.2011.08.088
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Kumar, K.S., Kumar, P.M., Reddy, M.A., Ferozuddin, M., Sreenivasulu, M., Jafar, A.A., Krishna, G.R., Reddy, C.M., Rambabu, D., Shiva Kumar, K., Pal, S., Pal, M. Yb(OTf)3 catalyzed new cascade reaction: A facile assembly of fused quinazolinones (2011) Chemical Communications, 47 (37), pp. 10263-10265. DOI: 10.1039/c1cc13695j
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Nakhi, A., Prasad, B., Reddy, U., Rao, R.M., Sandra, S., Kapavarapu, R., Rambabu, D., Rama Krishna, G., Reddy, C.M., Ravada, K., Misra, P., Iqbal, J., Pal, M. A new route to indoles via in situ desilylation-Sonogashira strategy: Identification of novel small molecules as potential anti-tuberculosis agents (2011) MedChemComm, 2 (10), pp. 1006-1010. DOI: 10.1039/c1md00148e
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Rajitha, C., Dubey, P.K., Sunku, V., Javier Piedrafita, F., Veeramaneni, V.R., Pal, M. Synthesis and pharmacological evaluations of novel 2H-benzo[b][1,4]oxazin- 3(4H)-one derivatives as a new class of anti-cancer agents (2011) European Journal of Medicinal Chemistry, 46 (10), pp. 4887-4896. DOI: 10.1016/j.ejmech.2011.07.045
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Parsa, K.V.L., Pal, M. Preclinical development of dipeptidyl peptidase IV inhibitor alogliptin: A brief overview (2011) Expert Opinion on Drug Discovery, 6 (8), pp. 855-869. DOI: 10.1517/17460441.2011.588695
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Layek, M., Syam Kumar, Y., Islam, A., Karavarapu, R., Sengupta, A., Halder, D., Mukkanti, K., Pal, M. Alkynylation of N-(3-iodopyridin-2-yl)sulfonamide under Pd/C-Cu catalysis: A direct one pot synthesis of 7-azaindoles and their pharmacological evaluation as potential inhibitors of sirtuins (2011) MedChemComm, 2 (6), pp. 478-485. DOI: 10.1039/c1md00029b
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Rao, R.M., Reddy Ch, U., Alinakhi, Mulakayala, N., Alvala, M., Arunasree, M.K., Poondra, R.R., Iqbal, J., Pal, M. Sequential coupling/desilylation-coupling/cyclization in a single pot under Pd/C-Cu catalysis: Synthesis of 2-(hetero) aryl indoles (2011) Organic and Biomolecular Chemistry, 9 (10), pp. 3808-3816. DOI: 10.1039/c0ob01161d
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Rambabu, D., Rama Krishna, G., Basavoju, S., Reddy, C.M., Pal, M. Crystal structure and synthesis of 4-(4-hydroxybenzylideneamino)-1-methyl-3-propyl-1H-pyrazole-5-carboxamide (2011) Journal of Molecular Structure, 994 (1-3), pp. 332-334. DOI: 10.1016/j.molstruc.2011.03.045
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Kumar, K.S., Kumar, P.M., Kumar, K.A., Sreenivasulu, M., Jafar, A.A., Rambabu, D., Krishna, G.R., Reddy, C.M., Kapavarapu, R., Shivakumar, K., Priya, K.K., Parsa, K.V.L., Pal, M. A new three-component reaction: Green synthesis of novel isoindolo[2,1-a]quinazoline derivatives as potent inhibitors of TNF-α (2011) Chemical Communications, 47 (17), pp. 5010-5012. DOI: 10.1039/c1cc10715a
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Gorja, D.R., Shiva Kumar, K., Mukkanti, K., Pal, M. C-C (alkynylation) vs C-O (ether) bond formation under Pd/C-Cu catalysis: Synthesis and pharmacological evaluation of 4-alkynylthieno[2,3-d]pyrimidines (2011) Beilstein Journal of Organic Chemistry, 7, pp. 338-345. DOI: 10.3762/bjoc.7.44
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Kumar, P.M., Kumar, K.S., Poreddy, S.R., Mohakhud, P.K., Mukkanti, K., Pal, M. Biginelli reaction beyond three-component limit: Synthesis of functionalized pyrimidinones via a one-pot Biginelli-Pd mediated C-C coupling strategy (2011) Tetrahedron Letters, 52 (11), pp. 1187-1191. DOI: 10.1016/j.tetlet.2011.01.015
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Pal, S., Chatare, V., Pal, M. Isocoumarin and its derivatives: An overview on their synthesis and applications (2011) Current Organic Chemistry, 15 (5), pp. 782-800. DOI: 10.2174/138527211794518970
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Layek, M., Reddy M., A., Dhanunjaya Rao, A.V., Alvala, M., Arunasree, M.K., Islam, A., Mukkanti, K., Iqbal, J., Pal, M. Transition metal mediated construction of pyrrole ring on 2,3-dihydroquinolin-4(1H)-one: Synthesis and pharmacological evaluation of novel tricyclic heteroarenes (2011) Organic and Biomolecular Chemistry, 9 (4), pp. 1004-1007. DOI: 10.1039/c0ob00771d
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Reddy, G.R., Reddy, T.R., Joseph, S.C., Reddy, K.S., Reddy, L.S., Kumar, P.M., Krishna, G.R., Reddy, C.M., Rambabu, D., Kapavarapu, R., Lakshmi, C., Meda, T., Priya, K.K., Parsa, K.V.L., Pal, M. Pd-mediated new synthesis of pyrroles: Their evaluation as potential inhibitors of phosphodiesterase 4 (2011) Chemical Communications, 47 (27), pp. 7779-7781. DOI: 10.1039/c1cc12321a
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Shroff, G.K., Kuna, R., Dirsipam, K., Yalagala, R., Mitra, P. Harnessing impaired energy metabolism in cancer cell: Small molecule- mediated ways to regulate tumorigenesis (2011) Anti-Cancer Agents in Medicinal Chemistry, 11 (3), pp. 272-279. DOI: 10.2174/187152011795347531
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Sreenivasulu, M., Arun Kumar, K., Sateesh Reddy, K., Siva Kumar, K., Rajender Kumar, P., Chandrasekhar, K.B., Pal, M. 1,3-Bis(2,4,6-trimethylphenyl) imidazolium chloride in combination with triethylamine: An improved catalytic system for hydroacylation/reduction of activated ketones (2011) Tetrahedron Letters, 52 (6), pp. 727-732. DOI: 10.1016/j.tetlet.2010.12.022
2010
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Arunkumar, K., Appi Reddy, M., Sravan Kumar, T., Vijaya Kumar, B., Chandrasekhar, K.B., Rajender Kumar, P., Pal, M. Achiral bis-imine in combination with CoCI2: A remarkable effect on enantioselectivity of lipasemediated acetylation of racemic secondary alcohol (2010) Beilstein Journal of Organic Chemistry, 6, pp. 1174-1179. DOI: 10.3762/bjoc.6.134
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Kalle, A.M., Mallika, A., Badiger, J., Alinakhi, Talukdar, P., Sachchidanand. Inhibition of SIRT1 by a small molecule induces apoptosis in breast cancer cells (2010) Biochemical and Biophysical Research Communications, 401 (1), pp. 13-19. DOI: 10.1016/j.bbrc.2010.08.118
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Vempati, R.K., Jayani, R.S., Notani, D., Sengupta, A., Galande, S., Haldar, D. p300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammals (2010) Journal of Biological Chemistry, 285 (37), pp. 28553-28564. DOI: 10.1074/jbc.M110.149393
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Lakshminarayana Reddy, C.N., Vyjayanti, V.N., Notani, D., Galande, S., Kotamraju, S. Down-regulation of the global regulator SATB1 by statins in COLO205 colon cancer cells (2010) Molecular Medicine Reports, 3 (5), pp. 857-861. DOI: 10.3892/mmr.2010.338
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Mulakayala, N., Reddy Ch, U., Iqbal, J., Pal, M. Synthesis of dipeptidyl peptidase-4 inhibitors: A brief overview (2010) Tetrahedron, 66 (27-28), pp. 4919-4938. DOI: 10.1016/j.tet.2010.04.088
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Mathew, R., Kruthiventi, A.K., Prasad, J.V., Kumar, S.P., Srinu, G., Chatterji, D. Inhibition of mycobacterial growth by plumbagin derivatives (2010) Chemical Biology and Drug Design, 76 (1), pp. 34-42. DOI: 10.1111/j.1747-0285.2010.00987
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Kumar, K.S., Chamakuri, S., Vishweshwar, P., Iqbal, J., Pal, M. AlCl3-induced (hetero)arylation of thienopyrimidine ring: a new synthesis of 4-substituted thieno[2,3-d]pyrimidines (2010) Tetrahedron Letters, 51 (25), pp. 3269-3273. DOI: 10.1016/j.tetlet.2010.04.057
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Venkata Prasad, J., Prabhakar, M., Manjulatha, K., Rambabu, D., Anand Solomon, K., Gopi Krishna, G., Anil Kumar, K. Efficient catalyst-free Domino approach for the synthesis of novel 2-benzazepine derivatives in water (2010) Tetrahedron Letters, 51 (23), pp. 3109-3111. DOI: 10.1016/j.tetlet.2010.04.020
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Rana, N., Moond, M., Marthi, A., Bapatla, S., Sarvepalli, T., Chatti, K., Challa, A.K. Caffeine-induced effects on heart rate in zebrafish embryos and possible mechanisms of action: An effective system for experiments in chemical biology (2010) Zebrafish, 7 (1), pp. 69-81. DOI: 10.1089/zeb.2009.0631
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Miglani, R., Cliffe, I.A., Voleti, S.R. Assessment of the putative binding conformation of a pyrazolopyridine class of inhibitors of MAPKAPK2 using computational studies (2010) European Journal of Medicinal Chemistry, 45 (1), pp. 98-105. DOI: 10.1016/j.ejmech.2009.09.030
2009
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Ande, S.R., Chen, J., Maddika, S. The ubiquitin pathway: An emerging drug target in cancer therapy (2009) European Journal of Pharmacology, 625 (1-3), pp. 199-205. DOI: 10.1016/j.ejphar.2009.08.042
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Kumar, K.S., Iqbal, J., Pal, M. Amberlyst-15: A mild, efficient and reusable heterogeneous catalyst for N-tert-butoxycarbonylation of amines (2009) Tetrahedron Letters, 50 (46), pp. 6244-6246. DOI: 10.1016/j.tetlet.2009.09.018
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Gorja, D.R., Batchu, V.R., Ettam, A., Pal, M. Pd/C-mediated synthesis of α-pyrone fused with a five-membered nitrogen heteroaryl ring: A new route to pyrano[4,3-c]pyrazol-4(1H)-ones (2009) Beilstein Journal of Organic Chemistry, 5. DOI: 10.3762/bjoc.5.64
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Rasheedi, S., Suragani, M., Haq, S.K., Ghosh, S., Ehtesham, N.Z., Hasnain, S.F. Biophysical characterization and unfolding of LEF4 factor of RNA polymerase from AcNPV (2009) Biopolymers, 91 (7), pp. 574-582. DOI: 10.1002/bip.21180
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Mehta, G., Talukdar, P., Pullepu, V., Sen, S. Conformationally restricted nucleocyclitols: A study into their conformational preferences and supramolecular architecture in the solid state (2009) European Journal of Organic Chemistry, (27), pp. 4691-4698. DOI: 10.1002/ejoc.200900611
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Mehta, G., Pallavi, K., Katukojvala, S. Cyclononitols: A flexible synthetic approach towards nine-membered carbasugar analogues (2009) Tetrahedron Letters, 50 (31), pp. 4519-4522. DOI: 10.1016/j.tetlet.2009.05.082
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Kalia, V., Miglani, R., Purnapatre, K.P., Mathur, T., Singhal, S., Khan, S., Voleti, S.R., Upadhyay, D.J., Singh Saini, K., Rattan, A., Raj, V.S. Mode of action of ranbezolid against staphylococci and structural modeling studies of its interaction with ribosomes (2009) Antimicrobial Agents and Chemotherapy, 53 (4), pp. 1427-1433. DOI: 10.1128/AAC.00887-08
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Kumar KS, Iqbal J, Pal M (2009). Amberlyst-15: a mild, efficient and reusable heterogeneous catalyst for N-tert-butoxycarbonylation of amines. Tetrahedron Letters, 50, 6244 – 6246.
2008
- Roy, S., Rajesh Goud, N., Jagadeesh Babu, N., Iqbal, J., Kruthiventi, A.K., Nangia, A. Crystal structures of norfloxacin hydrates (2008) Crystal Growth and Design, 8 (12), pp. 4343-4346. DOI: 10.1021/cg800519d